Publications

Showing records 1 - 20 (of 139)

Publication: Book Item (Buchkap., Lexikonartikel, jur. Kommentierung, Beiträge in Sammelbänden etc.)

ID	Author	Year	Title	Publisher
4498837	Boss, C.; Wittlin, S.	2018	Recent trends in malaria research	Division of Medicinal Chemistry

Publication: JournalArticle (Originalarbeit in einer wissenschaftlichen Zeitschrift)

ID	Author	Year	Title	Publisher
2088831	Brunner, R.; Ng, C. L.; Aissaoui, H.; Akabas, M. H.; Boss, C.; Brun, R.; Callaghan, P. S.; Corminboeuf, O.; Fidock, D. A.; Frame, I. J.; Heidmann, B.; Le Bihan, A.; Jeno, P.; Mattheis, C.; Moes, S.; Muller, I. B.; Paguio, M.; Roepe, P. D.; Siegrist, R.; Voss, Till S.; Welford, R. W.; Wittlin, S.; Binkert, C.	2013	UV-triggered affinity capture identifies interactions between the Plasmodium falciparum multidrug resistance protein 1 (PfMDR1) and antimalarial agents in live parasitized cells	Journal of biological chemistry
4485738	Brunschwig, Christel; Lawrence, Nina; Taylor, Dale; Abay, Efrem; Njoroge, Mathew; Basarab, Gregory S.; Le Manach, Claire; Paquet, Tanya; Cabrera, Diego Gonzàlez; Nchinda, Aloysius T.; de Kock, Carmen; Wiesner, Lubbe; Denti, Paolo; Waterson, David; Blasco, Benjamin; Leroy, Didier; Witty, Michael J.; Donini, Cristina; Duffy, James; Wittlin, Sergio; White, Karen L.; Charman, Susan A.; Jiménez-Díaz, Maria Belén; Angulo-Barturen, Iñigo; Herreros, Esperanza; Gamo, Francisco Javier; Rochford, Rosemary; Mancama, Dalu; Coetzer, Theresa L.; van der Watt, Mariëtte E.; Reader, Janette; Birkholtz, Lyn-Marie; Marsh, Kennan C.; Solapure, Suresh M.; Burke, John E.; McPhail, Jacob A.; Vanaerschot, Manu; Fidock, David A.; Fish, Paul V.; Siegl, Peter; Smith, Dennis A.; Wirjanata, Grennady; Noviyanti, Rintis; Price, Ric N.; Marfurt, Jutta; Silue, Kigbafori D.; Street, Leslie J.; Chibale, Kelly	2018	UCT943, a next generation Plasmodium falciparum PI4K inhibitor preclinical candidate for the treatment of malaria	Antimicrobial agents and chemotherapy
3644836	Norcross, Neil R; Baragaña, Beatriz; Wilson, Caroline; Hallyburton, Irene; Osuna-Cabello, Maria; Norval, Suzanne; Riley, Jennifer; Stojanovski, Laste; Simeons, Frederick R C; Porzelle, Achim; Grimaldi, Raffaella; Wittlin, Sergio; Duffy, Sandra; Avery, Vicky M; Meister, Stephan; Sanz, Laura; Jiménez-Díaz, Belén; Angulo-Barturen, Iñigo; Ferrer, Santiago; Martínez, María Santos; Gamo, Francisco Javier; Frearson, Julie A; Gray, David W; Fairlamb, Alan H; Winzeler, Elizabeth A; Waterson, David; Campbell, Simon F; Willis, Paul; Read, Kevin D; Gilbert, Ian H	2016	Trisubstituted Pyrimidines as Efficacious and Fast-Acting Antimalarials	Journal of Medicinal Chemistry
524647	Dong, Y.; Wittlin, S.; Sriraghavan, K.; Chollet, J.; Charman, S. A.; Charman, W. N.; Scheurer, C.; Urwyler, H.; Santo, T. J.; Snyder, C.; Creek, D. J.; Morizzi, J.; Koltun, M.; Matile, H.; Wang, X.; Padmanilayam, M.; Tang, Y.; Dorn, A.; Brun, R.; Vennerstrom, J. L.	2010	The structure-activity relationship of the antimalarial ozonide arterolane (OZ277)	Journal of Medicinal Chemistry
524646	Vennerstrom, J. L.	2010	The structure and antimalarial activity of dispiro-1,2,4,5-tetraoxanes derived from (+)-dihydrocarvone	Bioorganic and Medicinal Chemistry Letters
4700018	Davies, H.; Bergmann, B.; Walloch, P.; Nerlich, C.; Hansen, C.; Wittlin, S.; Spielmann, T.; Treeck, M.; Beitz, E.	2023	The plasmodium lactate/H+ transporter PfFNT is essential and druggable in vivo	Antimicrob Agents Chemother
524639	Tang, Yuanqing; Wittlin, Sergio; Charman, Susan A; Chollet, Jacques; Chiu, Francis C K; Morizzi, Julia; Johnson, Lisa M; Tomas, Josefina Santo; Scheurer, Christian; Snyder, Chistopher; Zhou, Lin; Dong, Yuxiang; Charman, William N; Matile, Hugues; Urwyler, Heinrich; Dorn, Arnulf; Vennerstrom, Jonathan L	2010	The comparative antimalarial properties of weak base and neutral synthetic ozonides	Bioorganic and Medicinal Chemistry Letters
4646371	Hitz, E.; Grüninger, O.; Passecker, A.; Wyss, M.; Scheurer, C.; Wittlin, S.; Beck, H. P.; Brancucci, N. M. B.; Voss, T. S.	2021	The catalytic subunit of Plasmodium falciparum casein kinase 2 is essential for gametocytogenesis	Commun Biol
4646227	Murithi, J. M.; Pascal, C.; Bath, J.; Boulenc, X.; Gnadig, N. F.; Pasaje, C. F. A.; Rubiano, K.; Yeo, T.; Mok, S.; Klieber, S.; Desert, P.; Jimenez-Diaz, M. B.; Marfurt, J.; Rouillier, M.; Cherkaoui-Rbati, M. H.; Gobeau, N.; Wittlin, S.; Uhlemann, A. C.; Price, R. N.; Wirjanata, G.; Noviyanti, R.; Tumwebaze, P.; Cooper, R. A.; Rosenthal, P. J.; Sanz, L. M.; Gamo, F. J.; Joseph, J.; Singh, S.; Bashyam, S.; Augereau, J. M.; Giraud, E.; Bozec, T.; Vermat, T.; Tuffal, G.; Guillon, J. M.; Menegotto, J.; Salle, L.; Louit, G.; Cabanis, M. J.; Nicolas, M. F.; Doubovetzky, M.; Merino, R.; Bessila, N.; Angulo-Barturen, I.; Baud, D.; Bebrevska, L.; Escudie, F.; Niles, J. C.; Blasco, B.; Campbell, S.; Courtemanche, G.; Fraisse, L.; Pellet, A.; Fidock, D. A.; Leroy, D.	2021	The antimalarial MMV688533 provides potential for single-dose cures with a high barrier to Plasmodium falciparum parasite resistance	Sci Transl Med
1635031	Delves, Michael; Plouffe, David; Scheurer, Christian; Meister, Stephan; Wittlin, Sergio; Winzeler, Elizabeth A; Sinden, Robert E; Leroy, Didier	2012	The activities of current antimalarial drugs on the life cycle stages of Plasmodium : a comparative study with human and rodent parasites	PLoS medicine
4665602	Walz, A.; Duffey, M.; Aljayyoussi, G.; Sax, S.; Leroy, D.; Besson, A.; Burrows, J. N.; Cherkaoui-Rbati, M. H.; Gobeau, N.; Westwood, M.-A.; Siethoff, C.; Gamo, S.; Mäser, P.; Wittlin, S.	2023	The Parasite Reduction Ratio (PRR) assay version 2: standardized assessment of Plasmodium falciparum viability after antimalarial treatment in vitro	Pharmaceuticals (Basel)
4646370	Hitz, E.; Wiedemar, N.; Passecker, A.; Graça, B. A. S.; Scheurer, C.; Wittlin, S.; Brancucci, N. M. B.; Vakonakis, I.; Mäser, P.; Voss, T. S.	2021	The 3-phosphoinositide-dependent protein kinase 1 is an essential upstream activator of protein kinase A in malaria parasites	PLoS Biol
1023082	Charman, Susan A; Arbe-Barnes, Sarah; Bathurst, Ian C; Brun, Reto; Campbell, Michael; Charman, William N; Chiu, Francis C K; Chollet, Jacques; Craft, J Carl; Creek, Darren J; Dong, Yuxiang; Matile, Hugues; Maurer, Melanie; Morizzi, Julia; Nguyen, Tien; Papastogiannidis, Petros; Scheurer, Christian; Shackleford, David M; Sriraghavan, Kamaraj; Stingelin, Lukas; Tang, Yuanqing; Urwyler, Heinrich; Wang, Xiaofang; White, Karen L; Wittlin, Sergio; Zhou, Lin; Vennerstrom, Jonathan L	2011	Synthetic ozonide drug candidate OZ439 offers new hope for a single-dose cure of uncomplicated malaria	Proceedings of the National Academy of Sciences of the United States of America
524632	Burgess, S. J.; Kelly, J. X.; Shomloo, S.; Wittlin, S.; Brun, R.; Liebmann, K.; Peyton, D. H.	2010	Synthesis, structure-activity relationship, and mode-of-action studies of antimalarial reversed chloroquine compounds	Journal of medicinal chemistry
3322665	Kaur, Gurminder; Singh, Kawaljit; Pavadai, Elumalai; Njoroge, Mathew; Espinoza-Moraga, Marlene; De Kock, Carmen; Smith, Peter J.; Wittlin, Sergio; Chibale, Kelly	2015	Synthesis of fusidic acid bioisosteres as antiplasmodial agents and molecular docking studies in the binding site of elongation factor-G	MedChemComm
1023081	Lu, Yue-Ting; Arai, Chika; Ge, Jian-Feng; Ren, Wu-Sheng; Kaiser, Marcel; Wittlin, Sergio; Brun, Reto; Lu, Jian-Mei; Ihara, Masataka	2011	Synthesis and in vitro antiprotozoal activities of water-soluble, inexpensive phenothiazinium chlorides	Dyes and pigments : an international journal
1023080	Shi, Xue-Liang; Ge, Jian-Feng; Liu, Bao-Qiang; Kaiser, Marcel; Wittlin, Sergio; Brun, Reto; Ihara, Masataka	2011	Synthesis and in vitro antiprotozoal activities of 5-phenyliminobenzo[a]phenoxazine derivatives	Bioorganic & medicinal chemistry letters : a Tetrahedron publication for the rapid dissemination of preliminary communications on all aspects of bioorganic chemistry, medicinal chemistry, bioinorganic chemistry and related disciplines
533420	Pudhom, Khanitha; Ge, Man-Feng; Arai, Chika; Yang, Mei; Kaiser, Marcel; Wittlin, Sergio; Brun, Reto; Itoh, Isamu; Ihara, Masataka	2009	Synthesis and biological properties of a rhodacyanine derivative, Ssj-127, having high efficacy against malaria protozoa	Heterocycles : an international journal for reviews and communications in heterocyclic chemistry
3749290	Espinoza-Moraga, Marlene; Singh, Kawaljit; Njoroge, Mathew; Kaur, Gurminder; Okombo, John; De Kock, Carmen; Smith, Peter J.; Wittlin, Sergio; Chibale, Kelly	2017	Synthesis and biological characterisation of ester and amide derivatives of fusidic acid as antiplasmodial agents	Bioorganic & medicinal chemistry

Showing records 1 - 20 (of 139)