Publications

Showing records 1 - 20 (of 139)

Publication: Book Item (Buchkap., Lexikonartikel, jur. Kommentierung, Beiträge in Sammelbänden etc.)

ID	Author	Year	Title	Publisher
4498837	Boss, C.; Wittlin, S.	2018	Recent trends in malaria research	Division of Medicinal Chemistry

Publication: JournalArticle (Originalarbeit in einer wissenschaftlichen Zeitschrift)

ID	Author	Year	Title	Publisher
524438	Abiodun, Oyindamola O.; Gbotosho, Grace O.; Ajaiyeoba, Edith O.; Happi, Christian T.; Hofer, Sandra; Wittlin, Sergio; Sowunmi, Akin; Brun, Reto; Oduola, Ayoade M. J.	2010	Comparison of SYBR Green I-, PicoGreen-, and [H-3]-hypoxanthine-based assays for in vitro antimalarial screening of plants from Nigerian ethnomedicine	Parasitology research : Organ der Deutschen Gesellschaft für Parasitologie
1572299	Abiodun, Oyindamola O; Brun, Reto; Wittlin, Sergio	2013	In vitro interaction of artemisinin derivatives or the fully synthetic peroxidic anti-malarial OZ277 with thapsigargin in Plasmodium falciparum strains	Malaria journal
4156982	Abla, Nada; Bashyam, Sridevi; Charman, Susan A.; Greco, Béatrice; Hewitt, Philip; Jiménez-Díaz, Maria Belén; Katneni, Kasiram; Kubas, Holger; Picard, Didier; Sambandan, Yuvaraj; Sanz, Laura; Smith, Dennis; Wang, Tai; Willis, Paul; Wittlin, Sergio; Spangenberg, Thomas	2017	Long-lasting and fast-acting in vivo efficacious antiplasmodial azepanylcarbazole amino alcohol	ACS medicinal chemistry letters
4500698	Attram, H. D.; Wittlin, S.; Chibale, K.	2019	Incorporation of an intramolecular hydrogen bonding motif in the side chain of antimalarial benzimidazoles	MedChemComm
4510075	Baartzes, N.; Stringer, T.; Seldon, R.; Warner, D. F.; Taylor, D.; Wittlin, S.; Chibale, K.; Smith, G. S.	2019	Bioisosteric ferrocenyl aminoquinoline-benzimidazole hybrids : antimicrobial evaluation and mechanistic insights	European journal of medicinal chemistry
3154657	Baragana, Beatriz; Hallyburton, Irene; Lee, Marcus C. S.; Norcross, Neil R.; Grimaldi, Raffaella; Otto, Thomas D.; Proto, William R.; Blagborough, Andrew M.; Meister, Stephan; Wirjanata, Grennady; Ruecker, Andrea; Upton, Leanna M.; Abraham, Tara S.; Almeida, Mariana J.; Pradhan, Anupam; Porzelle, Achim; Santos Martinez, Maria; Bolscher, Judith M.; Woodland, Andrew; Norval, Suzanne; Zuccotto, Fabio; Thomas, John; Simeons, Frederick; Stojanovski, Laste; Osuna-Cabello, Maria; Brock, Paddy M.; Churcher, Tom S.; Sala, Katarzyna A.; Zakutansky, Sara E.; Belen Jimenez-Diaz, Maria; Maria Sanz, Laura; Riley, Jennifer; Basak, Rajshekhar; Campbell, Michael; Avery, Vicky M.; Sauerwein, Robert W.; Dechering, Koen J.; Noviyanti, Rintis; Campo, Brice; Frearson, Julie A.; Angulo-Barturen, Inigo; Ferrer-Bazaga, Santiago; Javier Gamo, Francisco; Wyatt, Paul G.; Leroy, Didier; Siegl, Peter; Delves, Michael J.; Kyle, Dennis E.; Wittlin, Sergio; Marfurt, Jutta; Price, Ric N.; Sinden, Robert E.; Winzeler, Elizabeth A.; Charman, Susan A.; Bebrevska, Lidiya; Gray, David W.; Campbell, Simon; Fairlamb, Alan H.; Willis, Paul A.; Rayner, Julian C.; Fidock, David A.; Read, Kevin D.; Gilbert, Ian H.	2015	A novel multiple-stage antimalarial agent that inhibits protein synthesis	Nature
4501060	Baragaña, Beatriz; Forte, Barbara; Choi, Ryan; Nakazawa Hewitt, Stephen; Bueren-Calabuig, Juan A.; Pisco, João Pedro; Peet, Caroline; Dranow, David M.; Robinson, David A.; Jansen, Chimed; Norcross, Neil R.; Vinayak, Sumiti; Anderson, Mark; Brooks, Carrie F.; Cooper, Caitlin A.; Damerow, Sebastian; Delves, Michael; Dowers, Karen; Duffy, James; Edwards, Thomas E.; Hallyburton, Irene; Horst, Benjamin G.; Hulverson, Matthew A.; Ferguson, Liam; Jiménez-Díaz, María Belén; Jumani, Rajiv S.; Lorimer, Donald D.; Love, Melissa S.; Maher, Steven; Matthews, Holly; McNamara, Case W.; Miller, Peter; O'Neill, Sandra; Ojo, Kayode K.; Osuna-Cabello, Maria; Pinto, Erika; Post, John; Riley, Jennifer; Rottmann, Matthias; Sanz, Laura M.; Scullion, Paul; Sharma, Arvind; Shepherd, Sharon M.; Shishikura, Yoko; Simeons, Frederick R. C.; Stebbins, Erin E.; Stojanovski, Laste; Straschil, Ursula; Tamaki, Fabio K.; Tamjar, Jevgenia; Torrie, Leah S.; Vantaux, Amélie; Witkowski, Benoît; Wittlin, Sergio; Yogavel, Manickam; Zuccotto, Fabio; Angulo-Barturen, Iñigo; Sinden, Robert; Baum, Jake; Gamo, Francisco-Javier; Mäser, Pascal; Kyle, Dennis E.; Winzeler, Elizabeth A.; Myler, Peter J.; Wyatt, Paul G.; Floyd, David; Matthews, David; Sharma, Amit; Striepen, Boris; Huston, Christopher D.; Gray, David W.; Fairlamb, Alan H.; Pisliakov, Andrei V.; Walpole, Chris; Read, Kevin D.; Van Voorhis, Wesley C.; Gilbert, Ian H.	2019	Lysyl-tRNA synthetase as a drug target in malaria and cryptosporidiosis	Proceedings of the National Academy of Sciences of the United States of America
3749197	Baragaña, Beatriz; Norcross, Neil R.; Wilson, Caroline; Porzelle, Achim; Hallyburton, Irene; Grimaldi, Raffaella; Osuna-Cabello, Maria; Norval, Suzanne; Riley, Jennifer; Stojanovski, Laste; Simeons, Frederick R. C.; Wyatt, Paul G.; Delves, Michael J.; Meister, Stephan; Duffy, Sandra; Avery, Vicky M.; Winzeler, Elizabeth A.; Sinden, Robert E.; Wittlin, Sergio; Frearson, Julie A.; Gray, David W.; Fairlamb, Alan H.; Waterson, David; Campbell, Simon F.; Willis, Paul; Read, Kevin D.; Gilbert, Ian H.	2016	Discovery of a quinoline-4-carboxamide derivative with a novel mechanism of action, multistage antimalarial activity, and potent in vivo efficacy	Journal of medicinal chemistry
1027590	Barker, R. H. Jr.; Urgaonkar, S.; Mazitschek, R.; Celatka, C.; Skerlj, R.; Cortese, J. F.; Tyndall, E.; Liu, H.; Cromwell, M.; Sidhu, A. B.; Guerrero-Bravo, J. E.; Crespo-Llado, K. N.; Serrano, A. E.; Lin, J. W.; Janse, C. J.; Khan, S. M.; Duraisingh, M.; Coleman, B. I.; Angulo-Barturen, I.; Jimenez-Diaz, M. B.; Magan, N.; Gomez, V.; Ferrer, S.; Martinez, M. S.; Wittlin, S.; Papastogiannidis, P.; O'Shea, T.; Klinger, J. D.; Bree, M.; Lee, E.; Levine, M.; Wiegand, R. C.; Munoz, B.; Wirth, D. F.; Clardy, J.; Bathurst, I.; Sybertz, E.	2011	Aminoindoles, a novel scaffold with potent activity against Plasmodium falciparum	Antimicrobial agents and chemotherapy
3749532	Baumgärtner, Fabian; Jourdan, Joëlle; Scheurer, Christian; Blasco, Benjamin; Campo, Brice; Mäser, Pascal; Wittlin, Sergio	2017	In vitro activity of anti-malarial ozonides against an artemisinin-resistant isolate	Malaria journal
524559	Booker, Michael L; Bastos, Cecilia M; Kramer, Martin L; Barker, Robert H; Skerlj, Renato; Sidhu, Amar Bir; Deng, Xiaoyi; Celatka, Cassandra; Cortese, Joseph F; Guerrero Bravo, Jose E; Crespo Llado, Keila N; Serrano, Adelfa E; Angulo-Barturen, Iñigo; Jiménez-Díaz, María Belén; Viera, Sara; Garuti, Helen; Wittlin, Sergio; Papastogiannidis, Petros; Lin, Jing-Wen; Janse, Chris J; Khan, Shahid M; Duraisingh, Manoj; Coleman, Bradley; Goldsmith, Elizabeth J; Phillips, Margaret A; Munoz, Benito; Wirth, Dyann F; Klinger, Jeffrey D; Wiegand, Roger; Sybertz, Edmund	2010	Novel inhibitors of Plasmodium falciparum dihydroorotate dehydrogenase with anti-malarial activity in the mouse model	Journal of Biological Chemistry
4646512	Boss, C.; Wittlin, S.	2021	Our exciting journey to ACT-451840	Chimia
3645710	Boss, Christoph; Aissaoui, Hamed; Amaral, Nathalie; Bauer, Aude; Bazire, Stephanie; Binkert, Christoph; Brun, Reto; Bürki, Cédric; Ciana, Claire-Lise; Corminboeuf, Olivier; Delahaye, Stephane; Dollinger, Claire; Fischli, Christoph; Fischli, Walter; Flock, Alexandre; Frantz, Marie-Céline; Girault, Malory; Grisostomi, Corinna; Friedli, Astrid; Heidmann, Bibia; Hinder, Claire; Jacob, Gael; Le Bihan, Amelie; Malrieu, Sophie; Mamzed, Saskia; Merot, Aurelien; Meyer, Solange; Peixoto, Sabrina; Petit, Nolwenn; Siegrist, Romain; Trollux, Julien; Weller, Thomas; Wittlin, Sergio	2016	Discovery and characterization of ACT-451840 : an antimalarial drug with a novel mechanism of action	ChemMedChem
1634840	Brunner, R.; Aissaoui, H.; Boss, C.; Bozdech, Z.; Brun, R.; Corminboeuf, O.; Delahaye, S.; Fischli, C.; Heidmann, B.; Kaiser, M.; Kamber, J.; Meyer, S.; Papastogiannidis, P.; Siegrist, R.; Voss, Till S.; Welford, R.; Wittlin, S.; Binkert, C.	2012	Identification of a new chemical class of antimalarials	Journal of infectious diseases
2088831	Brunner, R.; Ng, C. L.; Aissaoui, H.; Akabas, M. H.; Boss, C.; Brun, R.; Callaghan, P. S.; Corminboeuf, O.; Fidock, D. A.; Frame, I. J.; Heidmann, B.; Le Bihan, A.; Jeno, P.; Mattheis, C.; Moes, S.; Muller, I. B.; Paguio, M.; Roepe, P. D.; Siegrist, R.; Voss, Till S.; Welford, R. W.; Wittlin, S.; Binkert, C.	2013	UV-triggered affinity capture identifies interactions between the Plasmodium falciparum multidrug resistance protein 1 (PfMDR1) and antimalarial agents in live parasitized cells	Journal of biological chemistry
4485738	Brunschwig, Christel; Lawrence, Nina; Taylor, Dale; Abay, Efrem; Njoroge, Mathew; Basarab, Gregory S.; Le Manach, Claire; Paquet, Tanya; Cabrera, Diego Gonzàlez; Nchinda, Aloysius T.; de Kock, Carmen; Wiesner, Lubbe; Denti, Paolo; Waterson, David; Blasco, Benjamin; Leroy, Didier; Witty, Michael J.; Donini, Cristina; Duffy, James; Wittlin, Sergio; White, Karen L.; Charman, Susan A.; Jiménez-Díaz, Maria Belén; Angulo-Barturen, Iñigo; Herreros, Esperanza; Gamo, Francisco Javier; Rochford, Rosemary; Mancama, Dalu; Coetzer, Theresa L.; van der Watt, Mariëtte E.; Reader, Janette; Birkholtz, Lyn-Marie; Marsh, Kennan C.; Solapure, Suresh M.; Burke, John E.; McPhail, Jacob A.; Vanaerschot, Manu; Fidock, David A.; Fish, Paul V.; Siegl, Peter; Smith, Dennis A.; Wirjanata, Grennady; Noviyanti, Rintis; Price, Ric N.; Marfurt, Jutta; Silue, Kigbafori D.; Street, Leslie J.; Chibale, Kelly	2018	UCT943, a next generation Plasmodium falciparum PI4K inhibitor preclinical candidate for the treatment of malaria	Antimicrobial agents and chemotherapy
2996091	Brücher, Karin; Gräwert, Tobias; Konzuch, Sarah; Held, Jana; Lienau, Claudia; Behrendt, Christoph; Illarionov, Boris; Maes, Louis; Bacher, Adelbert; Wittlin, Sergio; Mordmüller, Benjamin; Fischer, Markus; Kurz, Thomas	2015	Prodrugs of reverse fosmidomycin analogues	Journal of medicinal chemistry
4596372	Burgert, Lydia; Rottmann, Matthias; Wittlin, Sergio; Gobeau, Nathalie; Krause, Andreas; Dingemanse, Jasper; Möhrle, Jörg J.; Penny, Melissa A.	2020	Ensemble modeling highlights importance of understanding parasite-host behavior in preclinical antimalarial drug development	Scientific reports
524632	Burgess, S. J.; Kelly, J. X.; Shomloo, S.; Wittlin, S.; Brun, R.; Liebmann, K.; Peyton, D. H.	2010	Synthesis, structure-activity relationship, and mode-of-action studies of antimalarial reversed chloroquine compounds	Journal of medicinal chemistry

Showing records 1 - 20 (of 139)