Publications

Showing records 1 - 20 (of 139)

Publication: Book Item (Buchkap., Lexikonartikel, jur. Kommentierung, Beiträge in Sammelbänden etc.)

ID	Author	Year	Title	Publisher
4498837	Boss, C.; Wittlin, S.	2018	Recent trends in malaria research	Division of Medicinal Chemistry

Publication: JournalArticle (Originalarbeit in einer wissenschaftlichen Zeitschrift)

ID	Author	Year	Title	Publisher
4665554	Imlay, L. S.; Lawong, A. K.; Gahalawat, S.; Kumar, A.; Xing, C.; Mittal, N.; Wittlin, S.; Churchyard, A.; Niederstrasser, H.; Crespo-Fernandez, B.; Posner, B. A.; Gamo, F. J.; Baum, J.; Winzeler, E. A.; Laleu, B.; Ready, J. M.; Phillips, M. A.	2023	Fast-killing tyrosine amide ((S)-SW228703) with blood- and liver-stage antimalarial activity associated with the cyclic amine resistance locus (PfCARL)	ACS Infect Dis
4646114	Shackleford, D. M.; Chiu, F. C. K.; Katneni, K.; Blundell, S.; McLaren, J.; Wang, X.; Zhou, L.; Sriraghavan, K.; Alker, A. M.; Hunziker, D.; Scheurer, C.; Zhao, Q.; Dong, Y.; Mohrle, J. J.; Abla, N.; Matile, H.; Wittlin, S.; Vennerstrom, J. L.; Charman, S. A.	2021	Cytochrome P450-mediated metabolism and CYP Inhibition for the synthetic peroxide antimalarial OZ439	ACS Infect Dis
4646027	Wittlin, S.; Mäser, P.	2021	From magic bullet to magic bomb: reductive bioactivation of antiparasitic agents	ACS Infect Dis
4646199	Okaniwa, M.; Shibata, A.; Ochida, A.; Akao, Y.; White, K. L.; Shackleford, D. M.; Duffy, S.; Lucantoni, L.; Dey, S.; Striepen, J.; Yeo, T.; Mok, S.; Aguiar, A. C. C.; Sturm, A.; Crespo, B.; Sanz, L. M.; Churchyard, A.; Baum, J.; Pereira, D. B.; Guido, R. V. C.; Dechering, K. J.; Wittlin, S.; Uhlemann, A. C.; Fidock, D. A.; Niles, J. C.; Avery, V. M.; Charman, S. A.; Laleu, B.	2021	Repositioning and characterization of 1-(pyridin-4-yl)pyrrolidin-2-one derivatives as Plasmodium cytoplasmic prolyl-trna synthetase inhibitors	ACS Infect Dis
4646475	Cheuka, P. M.; Centani, L.; Arendse, L. B.; Fienberg, S.; Wambua, L.; Renga, S. S.; Dziwornu, G. A.; Kumar, M.; Lawrence, N.; Taylor, D.; Wittlin, S.; Coertzen, D.; Reader, J.; van der Watt, M.; Birkholtz, L. M.; Chibale, K.	2021	New amidated 3,6-diphenylated imidazopyridazines with potent antiplasmodium activity are dual inhibitors of; Plasmodium; phosphatidylinositol-4-kinase and cGMP-dependent protein kinase	ACS Infect Dis
4665573	Nguyen, W.; Dans, M. G.; Currie, I.; Awalt, J. K.; Bailey, B. L.; Lumb, C.; Ngo, A.; Favuzza, P.; Palandri, J.; Ramesh, S.; Penington, J.; Jarman, K. E.; Mukherjee, P.; Chakraborty, A.; Maier, A. G.; van Dooren, G. G.; Papenfuss, T.; Wittlin, S.; Churchyard, A.; Baum, J.; Winzeler, E. A.; Baud, D.; Brand, S.; Jackson, P. F.; Cowman, A. F.; Sleebs, B. E.	2023	7-N-substituted-3-oxadiazole quinolones with potent antimalarial activity target the cytochrome bc1 complex	ACS Infect Dis
4646303	Leas, D. A.; Sanford, A. G.; Wu, J.; Cal, M.; Kaiser, M.; Wittlin, S.; Hemsley, R. M.; Darner, E. B.; Lui, L. M.; Davis, P. H.; Vennerstrom, J. L.	2021	Diaryl ureas as an antiprotozoal chemotype	ACS Infect Dis
4523072	Jourdan, Joëlle; Walz, Annabelle; Matile, Hugues; Schmidt, Alexander; Wu, Jianbo; Wang, Xiaofang; Dong, Yuxiang; Vennerstrom, Jonathan L.; Schmidt, Remo S.; Wittlin, Sergio; Mäser, Pascal	2019	Stochastic protein alkylation by antimalarial peroxides	ACS Infectious Diseases
4651547	Dong, Y.; Sonawane, Y.; Maher, S. P.; Zeeman, A. M.; Chaumeau, V.; Vantaux, A.; Cooper, C. A.; Chiu, F. C. K.; Ryan, E.; McLaren, J.; Chen, G.; Wittlin, S.; Witkowski, B.; Nosten, F.; Sriraghavan, K.; Kyle, D. E.; Kocken, C. H. M.; Charman, S. A.; Vennerstrom, J. L.	2022	Metabolic, pharmacokinetic, and activity profile of the liver stage antimalarial (RC-12)	ACS Omega
3657113	Williamson, Alice E; Ylioja, Paul M; Robertson, Murray N; Antonova-Koch, Yevgeniya; Avery, Vicky; Baell, Jonathan B; Batchu, Harikrishna; Batra, Sanjay; Burrows, Jeremy N; Bhattacharyya, Soumya; Calderon, Felix; Charman, Susan A; Clark, Julie; Crespo, Benigno; Dean, Matin; Debbert, Stefan L; Delves, Michael; Dennis, Adelaide S M; Deroose, Frederik; Duffy, Sandra; Fletcher, Sabine; Giaever, Guri; Hallyburton, Irene; Gamo, Francisco-Javier; Gebbia, Marinella; Guy, R Kiplin; Hungerford, Zoe; Kirk, Kiaran; Lafuente-Monasterio, Maria J; Lee, Anna; Meister, Stephan; Nislow, Corey; Overington, John P; Papadatos, George; Patiny, Luc; Pham, James; Ralph, Stuart A; Ruecker, Andrea; Ryan, Eileen; Southan, Christopher; Srivastava, Kumkum; Swain, Chris; Tarnowski, Matthew J; Thomson, Patrick; Turner, Peter; Wallace, Iain M; Wells, Timothy N C; White, Karen; White, Laura; Willis, Paul; Winzeler, Elizabeth A; Wittlin, Sergio; Todd, Matthew H	2016	Open source drug discovery : highly potent antimalarial compounds derived from the tres cantos arylpyrroles	ACS central science
4499858	Kumar, Malkeet; Okombo, John; Mambwe, Dickson; Taylor, Dale; Lawrence, Nina; Reader, Janette; van der Watt, Mariëtte; Fontinha, Diana; Sanches-Vaz, Margarida; Bezuidenhout, Belinda C.; Lauterbach, Sonja B.; Liebenberg, Dale; Birkholtz, Lyn-Marie; Coetzer, Theresa L.; Prudêncio, Miguel; Egan, Timothy J.; Wittlin, Sergio; Chibale, Kelly	2019	Multistage antiplasmodium activity of astemizole analogues and inhibition of hemozoin formation as a contributor to their mode of action	ACS infectious diseases
4500098	Okombo, John; Brunschwig, Christel; Singh, Kawaljit; Dziwornu, Godwin Akpeko; Barnard, Linley; Njoroge, Mathew; Wittlin, Sergio; Chibale, Kelly	2019	Antimalarial pyrido[1,2-a]benzimidazole derivatives with mannich base side chains: synthesis, pharmacological evaluation and reactive metabolite trapping studies	ACS infectious diseases
3332923	Jourdan, Joëlle; Matile, Hugues; Reift, Ellen; Biehlmaier, Oliver; Dong, Yuxiang; Wang, Xiaofang; Mäser, Pascal; Vennerstrom, Jonathan L; Wittlin, Sergio	2016	Monoclonal antibodies that recognize the alkylation signature of antimalarial ozonides OZ277 (Arterolane) and OZ439 ( Artefenomel)	ACS infectious diseases
3396804	Wang, Xiaofang; Dong, Yuxiang; Cal, Monica; Kaiser, Marcel; Wittlin, Sergio; Vennerstrom, Jonathan L	2015	Antiprotozoal selectivity of diimidazoline N-phenylbenzamides	ACS infectious diseases
1022792	Schiaffo, Charles E.; Rottman, Matthias; Wittlin, Sergio; Dussault, Patrick H.	2011	3-alkoxy-1,2-dioxolanes : synthesis and evaluation as potential antimalarial agents	ACS medicinal chemistry letters
1023007	Skerlj, Renato T; Bastos, Cecilia M; Booker, Michael L; Kramer, Martin L; Barker, Robert H; Celatka, Cassandra A; O'Shea, Thomas J; Munoz, Benito; Sidhu, Amar Bir; Cortese, Joseph F; Wittlin, Sergio; Papastogiannidis, Petros; Angulo-Barturen, Inigo; Jimenez-Diaz, Maria Belen; Sybertz, Edmund	2011	Optimization of potent inhibitors of P. falciparum dihydroorotate dehydrogenase for the treatment of malaria	ACS medicinal chemistry letters
524460	Ge, Jian-Feng; Arai, Chika; Yang, Mei; Bakar Md, Abu; Lu, Jun; Ismail, Nasser S M; Wittlin, Sergio; Kaiser, Marcel; Brun, Reto; Charman, Susan A; Nguyen, Tien; Morizzi, Julia; Itoh, Isamu; Ihara, Masataka	2010	Discovery of novel benzo[a]phenoxazine SSJ-183 as a drug candidate for malaria	ACS medicinal chemistry letters
1634835	Edlin, Chris D; Morgans, Garreth; Winks, Susan; Duffy, Sandra; Avery, Vicky M; Wittlin, Sergio; Waterson, David; Burrows, Jeremy; Bryans, Justin	2012	Identification and in-vitro ADME assessment of a series of novel anti-malarial agents suitable for hit-to-lead chemistry	ACS medicinal chemistry letters
4156982	Abla, Nada; Bashyam, Sridevi; Charman, Susan A.; Greco, Béatrice; Hewitt, Philip; Jiménez-Díaz, Maria Belén; Katneni, Kasiram; Kubas, Holger; Picard, Didier; Sambandan, Yuvaraj; Sanz, Laura; Smith, Dennis; Wang, Tai; Willis, Paul; Wittlin, Sergio; Spangenberg, Thomas	2017	Long-lasting and fast-acting in vivo efficacious antiplasmodial azepanylcarbazole amino alcohol	ACS medicinal chemistry letters

Showing records 1 - 20 (of 139)