Publications
Showing records 21 - 40 (of 138)
Publication: JournalArticle (Originalarbeit in einer wissenschaftlichen Zeitschrift)
ID
Author
Year
Title
Publisher
160440 Spreafico, Morena; Ernst, Beat; Lill, Markus A.; Smiesko, Martin; Vedani, Angelo
2009
Mixed-Model QSAR at the Glucocorticoid Receptor: Predicting the Binding Mode and Affinity of Psychotropic Drugs
ChemMedChem
433351 Shelke, Sachin V; Cutting, Brian; Jiang, Xiaohua; Koliwer-Brandl, Hendrik; Strasser, Daniel S; Schwardt, Oliver; Kelm, Soerge; Ernst, Beat
2010
A Fragment-Based In Situ Combinatorial Approach To Identify High-Affinity Ligands for Unknown Binding Sites
Angewandte Chemie. International edition in English
3707431 Schönemann, Wojciech; Lindegger, Marcel; Rabbani, Said; Zihlmann, Pascal
2017
2-C-Branced mannosides as a novel family of FimH antagonists - Synthesis and biological evaluation
Perspectives in Science
3707410 Schönemann, Wojciech; Kleeb, Simon; Dätwyler, Philipp; Schwardt, Oliver; Ernst, Beat
2016
Prodruggability of Carbohydrates - Oral FimH Antagonists
Canadian Journal of Chemistry
4498507 Schönemann, Wojciech; Cramer, Jonathan; Mühlethaler, Tobias; Fiege, Brigitte; Silbermann, Marleen; Rabbani, Said; Dätwyler, Philipp; Zihlmann, Pascal; Jakob, Roman P.; Sager, Christoph P.; Smiesko, Martin; Schwardt, Oliver; Maier, Timm; Ernst, Beat
2019
Improvement of Aglycone π-Stacking Yields Nano- to Subnanomolar FimH Antagonists
ChemMedChem
1534723 Schwizer, Daniel; Patton, John T.; Cutting, Brian; Smiesko, Martin; Wagner, Beatrice; Kato, Ako; Weckerle, Céline; Binder, Florian P. C.; Rabbani, Said; Schwardt, Oliver; Magnani, John L.; Ernst, Beat
2012
Pre-organization of the core structure of E-selectin antagonists
Chemistry - A European Journal
765883 Schwardt, Oliver; Rabbani, Said; Hartmann, Margrit; Abgottspon, Daniela; Wittwer, Matthias; Kleeb, Simon; Zalewski, Adam; Smiesko, Martin; Cutting, Brian; Ernst, Beat
2011
Design, Synthesis and Biological Evaluation of Mannosyl Triazoles as FimH Antagonists
Bioorganic & Medicinal Chemistry
427694 Schwardt, Oliver; Koliwer-Brandl, Hendrik; Zimmerli, Raphael; Mesch, Stefanie; Rossato, Gianluca; Spreafico, Morena; Vedani, Angelo; Kelm, Sorge; Ernst, Beat
2010
Design, synthesis, biological evaluation and modeling of a non-carbohydrate antagonist of the myelin-associated glycoprotein
Bioorganic & Medicinal Chemistry
2291741 Schwardt, Oliver; Kelm, Soerge; Ernst, Beat
2015
SIGLEC-4 (MAG) Antagonists: From the Natural Carbohydrate Epitope to Glycomimetics
Topics in Current Chemistry
160452 Schwardt, Oliver; Gäthje, Heiko; Vedani, Angelo; Mesch, Stefanie; Gao, Gan-Pan; Spreafico, Morena; von Orelli, Johannes; Kelm, Sørge; Ernst, Beat
2009
Examination of the biological role of the a(2-6)-linked sialic acid in gangliosides binding to the myelin-associated glycoprotein (MAG)
Journal of Medicinal Chemistry
4606096 Scharf, Birte; Schmidt, Thomas J; Rabbani, Said; Stork, Christoph; Dobrindt, Ulrich; Sendker, Jandirk; Ernst, Beat; Hensel, Andreas
2020
Antiadhesive natural products against uropathogenic E. coli: What can we learn from cranberry extract?
Journal of ethnopharmacology
2291744 Scharenberg, Meike; Jiang, Xiaohua; Pang, Lijuan; Navarra, Giulio; Rabbani, Said; Binder, Florian; Schwardt, Oliver; Ernst, Beat
2013
Kinetic properties of carbohydrate–lectin interactions: FimH antagonists
ChemMedChem
765881 Scharenberg, Meike; Abgottspon, Daniela; Cicek, Evelin; Jiang, Xiaohua; Schwardt, Oliver; Rabbani, Said; Ernst, Beat
2011
A Flow Cytometry-based Assay for Screening FimH Antagonists
Assay and Drug Development Technologies
3449973 Sauer, Maximilian M; Jakob, Roman P; Eras, Jonathan; Baday, Sefer; Eriş, Deniz; Navarra, Giulio; Bernèche, Simon; Ernst, Beat; Maier, Timm; Glockshuber, Rudi
2016
Catch-bond mechanism of the bacterial adhesin FimH
Nature communications
4491494 Sauer, Maximilian M.; Jakob, Roman P.; Luber, Thomas; Canonica, Fabia; Navarra, Giulio; Ernst, Beat; Unverzagt, Carlo; Maier, Timm; Glockshuber, Rudi
2019
Binding of the bacterial adhesin FimH to its natural, multivalent high-mannose type glycan targets
Journal of the American Chemical Society
4029939 Sager, Christoph P.; Fiege, Brigitte; Zihlmann, Pascal; Vannam, Raghu; Rabbani, Said; Jakob, Roman P.; Preston, Roland C.; Zalewski, Adam; Maier, Timm; Peczuh, Mark W.; Ernst, Beat
2018
The price of flexibility - a case study on septanoses as pyranose mimetics
Chemical Science
4156329 Sager, Christoph P.; Eriş, Deniz; Smieško, Martin; Hevey, Rachel; Ernst, Beat
2017
What contributes to an effective mannose recognition domain?
Beilstein Journal of Organic Chemistry
427666 Rossato, Gianluca; Ernst, Beat; Smiesko, Martin; Spreafico, Morena; Vedani, Angelo
2010
Probing small-molecule binding to cytochrome P450 2D6 and 2C9: an in silico protocol for generating toxicity alerts
ChemMedChem
981870 Rossato, G.; Ernst, Beat; Vedani, Angelo; Smiesko, Martin
2011
AcquaAlta: a directional approach to the solvation of ligand-protein complexes
Journal of Chemical Information and Modeling
3707460 Rabbani, Said; Krammer, Eva-Maria; Goedele, Roos; Zalewski, Adam; Preston, Roland; Eid, Sameh; Zihlmann, Pascal; Prévost, Martine; Lensink, Marc F.; Thompson, Andrew; Ernst, Beat; Bouckaert, Julie
2017
Mutation of Tyr137 of the universal Escherichia coli fimbrial adhesin FimH relaxes the tyrosine gate prior to mannose binding
IU Cr J
Showing records 21 - 40 (of 138)
