Elucidation of the root immune response in a cellular and developmental context
Third-party funded project
Project title Elucidation of the root immune response in a cellular and developmental context
Principal Investigator(s) Boller, Thomas
Co-Investigator(s) Geldner, Niko
Métraux, Jean-Pierre
Hardtke, Christian
Project Members Koegel, Sally
Wyrsch, Ines
Hander, Tim
Organisation / Research unit Departement Umweltwissenschaften / Pflanzenphysiologie Pathogenabwehr (Boller)
Project start 01.10.2011
Probable end 30.09.2014
Status Completed
Abstract

Roots are the "the hidden half" of plants, buried in a soil environment in which they are incessantlyexposed to a large variety of microbes. Some of these microbes are pathogens, causing devastatingdiseases in crop production, but others are symbionts, promoting plant growth and serving the needs ofsustainable agroecosystems. Thus, plant roots should be able to mount an immune response towardspathogens, but at the same time they should not be offended by harmless rhizosphere microbes, and even open the doors to symbionts. How is this possible? We hypothesize that the precise cell-specific response to microbe-associated molecular patterns (MAMPs) and related signals has a major role to play, but there is currently a void in our knowledge about recognition, signalling and response in a cellular and developmental context.This project is a concerted effort to gain a molecular understanding of the interaction of roots withpathogens, put into the context of root structure and development. A network of four groups from threeSwiss Universities will undertake pioneering work in order to elucidate the distinct wiring and compartmentalisation of immune responses in roots. The teams will combine expertise of groups inplant-pathogen interactions (Boller and Metraux groups) with that of groups that are experts in rootdevelopment and cell biology (Hardtke and Geldner groups). Our aim is to undertake a molecular analysis of immune responses with cell-type and organ-specific resolution, taking into account the specific and dynamic structure of growing roots; its evolving mechanical barriers that will compartmentalise perception and response to pathogens; the molecular mechanisms that alter root growth and development upon attack and which, in turn, will influence susceptibility to pathogens.

Keywords Arabidopsis, plant pathogens, root development, endodermis
Financed by Swiss National Science Foundation (SNSF)

Cooperations ()

  ID Kreditinhaber Kooperationspartner Institution Laufzeit - von Laufzeit - bis
2362746  Boller, Thomas  Hardtke, Christian  Département de biologie moléculaire végétale, Université de Lausanne   01.08.2011  31.07.2014 
2362744  Boller, Thomas  Métraux, Jean-Pierre, Professor  Biologie Végétale, Université de Fribourg  01.08.2011  31.07.2014 
2362745  Boller, Thomas  Geldner, Niko, Professor  Département de biologie moléculaire végétale, Université de Lausanne  01.08.2011  31.07.2014 
   

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