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Allogeneic hematopoietic SCT as treatment option for patients with mitochondrial neurogastrointestinal encephalomyopathy (MNGIE): a consensus conference proposal for a standardized approach
JournalItem (Reviews, Editorials, Rezensionen, Urteilsanmerkungen etc. in einer wissenschaftlichen Zeitschrift)
 
ID 984353
Author(s) Halter, Joerg; Schüpbach, W. M. Michael; Casali, Carlo; Elhasid, Ronit; Fay, K.; Hammans, S.; Illa, I.; Kappeler, Liliane; Krähenbühl, Stephan; Lehmann, T.; Mandel, H.; Marti, Ramon; Mattle, Heinrich P.; Orchard, Kim; Savage, David; Sue, Carolyn M.; Valcarcel, David; Gratwohl, Alois; Hirano, M.
Author(s) at UniBasel Krähenbühl, Stephan
Year 2011
Title Allogeneic hematopoietic SCT as treatment option for patients with mitochondrial neurogastrointestinal encephalomyopathy (MNGIE): a consensus conference proposal for a standardized approach
Journal Bone marrow transplantation
Volume 46
Number 3
Pages 330-337
Mesh terms Humans; Intestinal Pseudo-Obstruction, surgery; Mitochondrial Encephalomyopathies, surgery; Muscular Dystrophy, Oculopharyngeal; Stem Cell Transplantation, standards
Abstract Allogeneic hematopoietic SCT (HSCT) has been proposed as a treatment for patients with mitochondrial neurogastrointestinal encephalomyopathy (MNGIE). HSCT has been performed in nine patients using different protocols with varying success. Based on this preliminary experience, participants of the first consensus conference propose a common approach to allogeneic HSCT in MNGIE. Standardization of the transplant protocol and the clinical and biochemical assessments will allow evaluation of the safety and efficacy of HSCT as well as optimization of therapy for patients with MNGIE.
Publisher Nature Publishing Group
ISSN/ISBN 0268-3369 ; 1476-5365
edoc-URL https://edoc.unibas.ch/64267/
Full Text on edoc No
Digital Object Identifier DOI 10.1038/bmt.2010.100
PubMed ID http://www.ncbi.nlm.nih.gov/pubmed/20436523
ISI-Number 000288164000002
Document type (ISI) Consensus Development Conference, Journal Article
 
   

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