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Mechanism of action of MDMA (Ecstasy)
Project funded by own resources |
Project title |
Mechanism of action of MDMA (Ecstasy) |
Principal Investigator(s) |
Liechti, Matthias Emanuel
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Co-Investigator(s) |
Huwyler, Jörg Brenneisen, Rudolf
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Project Members |
Hysek, Cédric Simmler, Linda Nicola, Valentina Giulia Ineichen, Martina
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Organisation / Research unit |
Bereich Medizinische Fächer (Klinik) / Klinische Pharmakologie (Krähenbühl) |
Project start |
01.10.2009 |
Probable end |
31.12.2014 |
Status |
Completed |
Abstract |
In our main project: “Mechanism of action of MDMA (Ecstasy)” we investigate how MDMA acts in the brain using both in vitro techniques and studies in humans. In the in vitro studies we assess interactions of MDMA with serotonin-, dopamine-, and norepinephrine uptake carriers in cell assays. In humans, we assess the subjective and cardiovascular effects of MDMA after the administration of substances that selectively block potential sites of action of MDMA in the brain. |
Financed by |
University funds Other funds
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28/03/2024
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