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Mechanism of action of MDMA (Ecstasy)
Project funded by own resources
Project title Mechanism of action of MDMA (Ecstasy)
Principal Investigator(s) Liechti, Matthias Emanuel
Co-Investigator(s) Huwyler, Jörg
Brenneisen, Rudolf
Project Members Hysek, Cédric
Simmler, Linda
Nicola, Valentina Giulia
Ineichen, Martina
Organisation / Research unit Bereich Medizinische Fächer (Klinik) / Klinische Pharmakologie (Krähenbühl)
Project start 01.10.2009
Probable end 31.12.2014
Status Completed
Abstract

In our main project: “Mechanism of action of MDMA (Ecstasy)” we investigate how MDMA acts in the brain using both in vitro techniques and studies in humans. In the in vitro studies we assess interactions of MDMA with serotonin-, dopamine-, and norepinephrine uptake carriers in cell assays. In humans, we assess the subjective and cardiovascular effects of MDMA after the administration of substances that selectively block potential sites of action of MDMA in the brain.

Financed by University funds
Other funds
   

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