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Prenatal alcohol exposure and long-term developmental consequences
JournalArticle (Originalarbeit in einer wissenschaftlichen Zeitschrift)
 
ID 79792
Author(s) Spohr, H. L.; Willms, J.; Steinhausen, Hans-Christoph
Author(s) at UniBasel Steinhausen, Hans-Christoph
Year 1993
Title Prenatal alcohol exposure and long-term developmental consequences
Journal Lancet
Volume 341
Number 8850
Pages / Article-Number 907-10
Abstract Fetal alcohol syndrome (FAS) is a leading cause of congenital mental retardation but little is known about the long-term development and adolescent outcome of children with FAS. In a 10-year follow-up study of 60 patients diagnosed as having FAS in infancy and childhood, we investigated the long-term sequelae of intrauterine alcohol exposure. We found that the characteristic craniofacial malformations of FAS diminish with time, but microcephaly and, to a lesser degree, short stature and underweight (in boys) persist; in female adolescents body weight normalises. Persistent mental retardation is the major sequela of intrauterine alcohol exposure in many cases, and environmental and educational factors do not have strong compensatory effects on the intellectual development of affected children.
Publisher Elsevier
ISSN/ISBN 0140-6736 ; 1474-547X
edoc-URL http://edoc.unibas.ch/dok/A5838974
Full Text on edoc No
Digital Object Identifier DOI 10.1016/0140-6736(93)91207-3
PubMed ID http://www.ncbi.nlm.nih.gov/pubmed/7681518
ISI-Number WOS:A1993KW98100001
Document type (ISI) Journal Article
 
   

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