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BRIGHT - Building Research Initiative Group: Chronic Illness Management and adherence in Transplantation
Third-party funded project |
Project title |
BRIGHT - Building Research Initiative Group: Chronic Illness Management and adherence in Transplantation |
Principal Investigator(s) |
De Geest, Sabina M. Dobbels, Fabienne
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Project Members |
Berben, Lut Denhaerynck, Kris Luta, Xhyljeta Awad, Remon Saeed Helmy
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Organisation / Research unit |
Departement Public Health / Pflegewissenschaft (De Geest) |
Project start |
01.01.2012 |
Probable end |
31.12.2018 |
Status |
Completed |
Abstract |
Interventional pathways to improve long term outcome after heart transplantation (HTx) will be dependent on better understanding of behavioral and care system interventional pathways. The BRIGHT study is an unique intercontinental study in 11 countries, 36 HTx centers and 1397 patients to assess the variability in practice patterns in HTx long term follow-up as well as the prevalence and variability in non-adherence to health behaviors. The BRIGHT study assesses aspects of HTx care at different levels of the health care system (patient, health care provider/family, transplant center, health policy/health care system). Multilevel factors related to medication non-adherence were therefore also assessed for the 1st time.. Targets: 1. To describe chronic illness management practice patterns among centers, countries, and continents in heart transplantation. 2. To assess the prevalence and variability of non-adherence to treatment regimens, i.e. medication taking, smoking cessation, diet keeping, alcohol consumption, physical activity, sun protection, and appointment keeping in heart transplant recipients among centers, countries, and continents. 3. To determine which multi-level factors are related to immunosuppressive medication adherence at the patient, provide, health care organization and health care system level To benchmark participating centers, countries, and continents in relation to chronic illness management practice patterns and non-adherence to health behaviors. The study used a cross-sectional survey design in 36 heart transplant centers covering 11 countries in 4 continents. It used 4 questionnaires; 1 for the director of each heart transplant center, 1 for the clinicians at each center, and 2 for each heart transplant recipient (interview and self-administered), in addition to collecting clinical information on each heart transplant recipient and a collateral report by the clinicians on patients’ medication adherence. The BRIGHT study’s findings will provide indication for leverage points to develop behavioral and care system interventional pathways to improve long term outcomes after HTx |
Financed by |
Foundations and Associations
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Published results () |
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ID |
Autor(en) |
Titel |
ISSN / ISBN |
Erschienen in |
Art der Publikation |
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3975237 |
Berben, Lut; Denhaerynck, Kris; Dobbels, Fabienne; Engberg, Sandra; Vanhaecke, Johan; Crespo-Leiro, Maria G.; Russell, Cynthia L.; De Geest, Sabina; Bright study consortium, |
Building research initiative group: chronic illness management and adherence in transplantation (BRIGHT) study: study protocol |
0309-2402 ; 1365-2648 |
Journal of Advanced Nursing |
Publication: JournalArticle (Originalarbeit in einer wissenschaftlichen Zeitschrift) |
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3999761 |
Berben, Lut; Russell, Cynthia L.; Engberg, Sandra; Dobbels, Fabienne; De Geest, Sabina M. |
Development, content validity and inter-rater reliability testing of the CIMI-BRIGHT: an instrument to assess the level of chronic illness management implemented in solid organ transplant programs |
2053-4345 ; 2053-4353 |
International Journal of Care Coordination |
Publication: JournalArticle (Originalarbeit in einer wissenschaftlichen Zeitschrift) |
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4267451 |
Cajita, Maan Isabella; Baumgartner, Eva; Berben, Lut; Denhaerynck, Kris; Helmy, Remon; Schönfeld, Sandra; Berger, Gabriele; Vetter, Christine; Dobbels, Fabienne; Russell, Cynthia L.; De Geest, Sabina; Bright Study Team, |
Heart transplant centers with multidisciplinary team show a higher level of chronic illness management - Findings from the International BRIGHT Study |
0147-9563 ; 1527-3288 |
Heart and Lung |
Publication: JournalArticle (Originalarbeit in einer wissenschaftlichen Zeitschrift) |
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4267468 |
Cajita, Maan Isabella; Denhaerynck, Kris; Dobbels, Fabienne; Berben, Lut; Russell, Cynthia L.; Davidson, Patricia M.; De Geest, Sabina |
Health literacy in heart transplantation: Prevalence, correlates and associations with health behaviors-Findings from the international BRIGHT study |
1053-2498 ; 1557-3117 |
The Journal of Heart and Lung Transplantation |
Publication: JournalArticle (Originalarbeit in einer wissenschaftlichen Zeitschrift) |
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4267473 |
Cajita, Maan Isabella; Baumgartner, E. Regula; Berben, Lut; Denhaerynck, Kris; Helmy, Remon; Schönfeld, S.; Berger, Gregor; Vetter, Christine; Dobbels, Fabienne; Russell, Cynthia L.; De Geest, Sabina; The Bright Study Team, |
Do heart transplant centers have a multidisciplinary team as indicated by ISHLT guidelines? – Findings from the International BRIGHT Study |
1053-2498 ; 1557-3117 |
Journal of Heart and Lung Transplantation |
Publication: JournalArticle (Originalarbeit in einer wissenschaftlichen Zeitschrift) |
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4491164 |
Helmy, Remon; Duerinckx, Nathalie; De Geest, Sabina; Denhaerynck, Kris; Berben, Lut; Russell, Cynthia L.; Van Cleemput, Johan; Crespo-Leiro, Maria G.; Dobbels, Fabienne; Bright study team, |
The international prevalence and variability of nonadherence to the nonpharmacologic treatment regimen after heart transplantation: Findings from the cross-sectional BRIGHT study |
1399-0012 |
Clinical transplantation |
Publication: JournalArticle (Originalarbeit in einer wissenschaftlichen Zeitschrift) |
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4495075 |
Denhaerynck, Kris; Berben, Lut; Dobbels, Fabienne; Russell, Cynthia L.; Crespo-Leiro, Marisa G.; Poncelet, Alain Jean; De Geest, Sabina |
Multilevel factors are associated with immunosuppressant nonadherence in heart transplant recipients: The international BRIGHT study |
1600-6135 |
American journal of transplantation |
Publication: JournalArticle (Originalarbeit in einer wissenschaftlichen Zeitschrift) |
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4495078 |
Duerinckx N, De Geest S.; Denhaerynck K, Berben L.; Vanhaecke J, Russell C.; Helmy R, Crespo-Leiro M.; Dobbels, F. |
Variability in Depressive Symptoms and Its Multilevel Correlates in Heart Transplant Recipients: Results From the International Cross-sectional BRIGHT Study |
1053-2498 ; 1557-3117 |
Journal of Heart and Lung Transplantation |
Publication: JournalArticle (Originalarbeit in einer wissenschaftlichen Zeitschrift) |
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4495112 |
Senft, Yuliya; Kirsch, Monika; Denhaerynck, Kris; Dobbels, Fabienne; Helmy, Remon; Russell, Cynthia L.; Berben, Lut; De Geest, Sabina |
Practice patterns to improve pre and post-transplant medication adherence in heart transplant centres: a secondary data analysis of the international BRIGHT study |
1474-5151 ; 1873-1953 |
European Journal of Cardiovascular Nursing |
Publication: JournalArticle (Originalarbeit in einer wissenschaftlichen Zeitschrift) |
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4501683 |
Helmy, Remon; de Almeida, Samira Scalso; Denhaerynck, Kris; Berben, Lut; Dobbels, Fabienne; Russell, Cynthia L.; Roza, Bartira de Aguiar; De Geest, Sabina; Crespo-Leiro, Marisa G.; Guppies, Sandra; De Simone, Paolo; Groenewoud, Albert; Kugler, Christiane; Ohler, Linda; Van Cleemput, Johan; Poncelet, Alain Jean; Sebbag, Laurent; Michel, Magali; Bernard, Andree; Doesch, Andreas; Livi, Ugolino; Potena, Luciano; Brossa-Loidi, Vicens; Segovia-Cubero, Javier; Almenar-Bonet, Luis; Segura Saint-Gerons, Carmen; Mohacsi, Paul; Horvath, Eva; Riotto, Cheryl; Parry, Gareth; Firouzi, Ashi; Kozuszko, Stella; Haddad, Haissam; Kaan, Annemarie; Fisher, Grant; Miller, Tara; Flattery, Maureen; Ludrosky, Kristin; Albert, Nancy; Coleman, Bernice; Trammell, Jacqueline; Epstein, Flavio; St Clair, Katherine; Kao, Andrew; Molina, Maria; Canales, Karyn Ryan; de Almeida, Samira Scalso; Ayoub, Andrea Cotait; Barone, Fernanda; Harkess, Michelle; Maddicks-Law, Joanne; Bright Study Team, |
Prevalence of Medication Nonadherence to Co-medication Compared to Immunosuppressants in Heart Transplant Recipients: Findings From the International Cross-sectional BRIGHT Study |
0149-2918 ; 1879-114X |
Clinical therapeutics |
Publication: JournalArticle (Originalarbeit in einer wissenschaftlichen Zeitschrift) |
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4501687 |
Alrawashdeh, M.; Molina, M. R.; Beckmann, S.; Denhaerynck, K.; Dobbels, F.; De Geest, S. |
The BRIGHT Study Shows Geographical Disparities in Body Mass Index among Heart Transplant Recipients |
1053-2498 |
The Journal of Heart and Lung Transplantation |
Publication: Other Publications (Forschungsberichte o. ä.) |
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4530638 |
Alaerts, Ellen; Dreesen, Carolien; Denhaerynck, Kris; Gryp, Sabine; Van Cleemput, Johan; Schuermans, Annette; Russell, Cynthia L.; Dobbels, Fabienne; De Geest, Sabina; Bright study team, |
Variability in practice patterns regarding protective isolation measures after heart transplantation: A secondary analysis of the international BRIGHT study |
0196-6553 ; 1527-3296 |
American journal of infection control |
Publication: JournalArticle (Originalarbeit in einer wissenschaftlichen Zeitschrift) |
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4597489 |
Iglesias, Katia; De Geest, Sabina; Berben, Lut; Dobbels, Fabienne; Denhaerynk, Kris; Russell, L. Cynthia; Helmy, Remon; Peytremann-Bridevaux, Isabelle; Bright study team, |
Validation of the patient assessment of chronic illness care (PACIC) short form scale in heart transplant recipients: the international cross-sectional bright study |
1472-6963 |
BMC Health Services Research |
Publication: JournalArticle (Originalarbeit in einer wissenschaftlichen Zeitschrift) |
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