An outbreak of the desert sub-type of zoonotic visceral leishmaniasis in Jiashi, Xinjiang Uygur Autonomous Region, People's Republic of China
JournalArticle (Originalarbeit in einer wissenschaftlichen Zeitschrift)
 
ID 524395
Author(s) Wang, Jun-Yun; Gao, Chun-Hua; Yang, Yue-Tao; Chen, Hai-Tang; Zhu, Xue-Hua; Lv, Shan; Chen, Sheng-Bang; Tong, Su-Xiang; Steinmann, Peter; Ziegelbauer, Kathrin; Zhou, Xiao-Nong
Author(s) at UniBasel Steinmann, Peter
Year 2010
Title An outbreak of the desert sub-type of zoonotic visceral leishmaniasis in Jiashi, Xinjiang Uygur Autonomous Region, People's Republic of China
Journal Parasitology International
Volume 59
Number 3
Pages / Article-Number 331-7
Keywords Visceral leishmaniasis, Outbreak, Leishmania donovani, Leishmania infantum, China
Abstract Few outbreaks of the desert sub-type of zoonotic visceral leishmaniasis (VL) have been described worldwide. In 2008, the incidence rate of VL in Jiashi County, Xinjiang Uygur Autonomous Region in the western part of the People's Republic of China, increased more than twenty-folds compared to the average annual incidence rate. The majority of the cases (96.6%) occurred among <2 year-old infants. For the first time in the desert area of Xinjiang, the parasites were isolated from bone marrow aspirates, using the NNN medium culture approach. The genetic analysis of the ITS-1 nucleotide sequence indicated that three isolates from eastern Jiashi County were genetically closely related and belonged to the Leishmaniainfantum group. However, they differed from an isolate from Kashi city which was classified as a member of the Leishmaniadonovani group
Publisher Elsevier
ISSN/ISBN 1383-5769
edoc-URL http://edoc.unibas.ch/dok/A5842809
Full Text on edoc No
Digital Object Identifier DOI 10.1016/j.parint.2010.04.002
PubMed ID http://www.ncbi.nlm.nih.gov/pubmed/20434585
ISI-Number WOS:000281461500005
Document type (ISI) Journal Article
 
   

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