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BattleX: Manipulating the fight between human host cells and intracellular pathogens
Third-party funded project |
Project title |
BattleX: Manipulating the fight between human host cells and intracellular pathogens |
Principal Investigator(s) |
Bumann, Dirk
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Co-Investigator(s) |
Arrieumerlou, Cécile Bairoch, Amos Hatzimanikatis, Vassily Schlapbach, Ralph Vorholt, Julia
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Project Members |
Freed, Nicole Kentner, David Chiquet, Petra Benzies, Rachel Limenitakis, Julien Burton, Olga
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Organisation / Research unit |
Departement Biozentrum / Molecular Microbiology (Bumann) |
Project Website |
https://www.battlex.org/ |
Project start |
01.01.2010 |
Probable end |
31.12.2013 |
Status |
Completed |
Abstract |
The goal of the BattleX project is to combine accurate genome-scale models of both host and pathogen that will pave the way for an integrated comprehensive understanding of infectious diseases as a rational basis to develop urgently needed control strategies. It is a Research, Technology and Development (RTD) project, funded by SystemsX.ch, the Swiss Initiative in Systems Biology.
We aim to develop novel strategies to combat infections; specifically, to identify novel targets/target combinations in metabolism for control of shigellosis, focusing on one infection model, intracellular Shigella infection of human cells. This model is medically relevant and offers unique advantages for a systems approach. |
Keywords |
metabolism, infectious diseases, intracellular passages |
Financed by |
Swiss Government (Research Cooperations)
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Cooperations () |
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ID |
Kreditinhaber |
Kooperationspartner |
Institution |
Laufzeit - von |
Laufzeit - bis |
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474805 |
Bumann, Dirk |
Palsson, Bernhard, Professor |
University of California in San Diego, Department of Bioengineering |
01.01.2010 |
31.12.2013 |
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25/04/2024
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