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Identification of kinase inhibitors of biogenic origin
Project funded by own resources |
Project title |
Identification of kinase inhibitors of biogenic origin |
Principal Investigator(s) |
Hamburger, Matthias Meijer, Laurent
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Co-Investigator(s) |
Potterat, Olivier
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Project Members |
Grabher, Patrick
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Organisation / Research unit |
Departement Pharmazeutische Wissenschaften / Pharmazeutische Biologie (Hamburger) |
Project start |
16.01.2009 |
Probable end |
31.12.2012 |
Status |
Completed |
Abstract |
An in house extract library is screened in a panel of kinase assays. Emphasis is on kinases involved in cell cycle regulation and in neurodegeneration. Active compounds are identified via HPLC-based activity profiling and in-line and off-line spectroscopic characterization. Selectivity of compounds and their drug-likeness is assessed. Selected molecules may serve as starting points for drug development. |
Financed by |
Other funds
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Cooperations () |
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ID |
Kreditinhaber |
Kooperationspartner |
Institution |
Laufzeit - von |
Laufzeit - bis |
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169723 |
Hamburger, Matthias |
Laurent Meijer, Prof. |
CNRS, Roscoff, Groupe Cycle Cellulaire |
16.02.2009 |
31.12.2013 |
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470279 |
Hamburger, Matthias |
Skaltsounis Leandros, Prof. |
University of Athens, Faculty of Pharmacy |
16.02.2009 |
31.12.2013 |
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29/03/2024
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