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Antiproliferative properties: search for natural products with pathway selective and synergistic effects
Project funded by own resources |
Project title |
Antiproliferative properties: search for natural products with pathway selective and synergistic effects |
Principal Investigator(s) |
Hamburger, Matthias Moroni, Christoph
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Co-Investigator(s) |
Potterat, Olivier
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Project Members |
Guldbrandsen, Niels Colombi, Marco
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Organisation / Research unit |
Departement Pharmazeutische Wissenschaften / Pharmazeutische Biologie (Hamburger), Departement Biozentrum / Growth and Development (Moroni) |
Project start |
01.01.2010 |
Probable end |
30.06.2012 |
Status |
Completed |
Abstract |
An extract library is screened in a panel of cell constructs enabling characterization of pathway selective antiproliferative action. Active compounds are identified via HPLC-based activity profiling and in-line and off-line spectroscopic characterization. Synergistic action with known drugs is being tracked with the same approach. The goal is to identfy and further characterize new scaffolds that could serve as tools or as starting point for drug development. |
Financed by |
Other funds
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Cooperations () |
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ID |
Kreditinhaber |
Kooperationspartner |
Institution |
Laufzeit - von |
Laufzeit - bis |
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462205 |
Hamburger, Matthias |
Christoph Moroni, Prof. |
University of Basel |
01.01.2010 |
31.12.2011 |
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29/03/2024
Research Database / FORSCHUNGSDATENBANK
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