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Self-reported life-space mobility in the first year after ischemic stroke: longitudinal findings from the MOBITEC-Stroke project.
JournalArticle (Originalarbeit in einer wissenschaftlichen Zeitschrift)
ID 4697912
Author(s) Hinrichs, Timo; Rössler, Roland; Infanger, Denis; Weibel, Robert; Schär, Janine; Peters, Eva-Maria; Portegijs, Erja; Rantanen, Taina; Schmidt-Trucksäss, Arno; Engelter, Stefan T; Peters, Nils
Author(s) at UniBasel Hinrichs, Timo
Year 2023
Title Self-reported life-space mobility in the first year after ischemic stroke: longitudinal findings from the MOBITEC-Stroke project.
Journal Journal of neurology
Volume 270
Number 8
Pages / Article-Number 3992-4003
Keywords Cohort studies; Mobility limitation; Physical functional performance; Social participation; Spatial behavior
Mesh terms Humans; Female; Aged; Male; Activities of Daily Living; Self Report; Cohort Studies; Ischemic Stroke; Mobility Limitation; Stroke, epidemiology

Life-space mobility is defined as the size of the area in which a person moves about within a specified period of time. Our study aimed to characterize life-space mobility, identify factors associated with its course, and detect typical trajectories in the first year after ischemic stroke.; MOBITEC-Stroke (ISRCTN85999967; 13/08/2020) was a cohort study with assessments performed 3, 6, 9 and 12 months after stroke onset. We applied linear mixed effects models (LMMs) with life-space mobility (Life-Space Assessment; LSA) as outcome and time point, sex, age, pre-stroke mobility limitation, stroke severity (National Institutes of Health Stroke Scale; NIHSS), modified Rankin Scale, comorbidities, neighborhood characteristics, availability of a car, Falls Efficacy Scale-International (FES-I), and lower extremity physical function (log-transformed timed up-and-go; TUG) as independent variables. We elucidated typical trajectories of LSA by latent class growth analysis (LCGA) and performed univariate tests for differences between classes.; In 59 participants (mean age 71.6, SD 10.0 years; 33.9% women), mean LSA at 3 months was 69.3 (SD 27.3). LMMs revealed evidence (p ≤ 0.05) that pre-stroke mobility limitation, NIHSS, comorbidities, and FES-I were independently associated with the course of LSA; there was no evidence for a significant effect of time point. LCGA revealed three classes: "low stable", "average stable", and "high increasing". Classes differed with regard to LSA starting value, pre-stroke mobility limitation, FES-I, and log-transformed TUG time.; Routinely assessing LSA starting value, pre-stroke mobility limitation, and FES-I may help clinicians identify patients at increased risk of failure to improve LSA.

ISSN/ISBN 1432-1459
Full Text on edoc
Digital Object Identifier DOI 10.1007/s00415-023-11748-5
PubMed ID

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