Data Entry: Please note that the research database will be replaced by UNIverse by the end of October 2023. Please enter your data into the system https://universe-intern.unibas.ch. Thanks

Login for users with Unibas email account...

Login for registered users without Unibas email account...

 
Epidemiology of pediatric schistosomiasis in hard-to-reach areas and populations: a scoping review protocol
JournalArticle (Originalarbeit in einer wissenschaftlichen Zeitschrift)
 
ID 4662799
Author(s) Isaiah, P. M.; Palmeirim, M. S.; Steinmann, P.
Author(s) at UniBasel Isaiah, Phyllis
Sólveig Palmeirim, Marta
Steinmann, Peter
Year 2023
Title Epidemiology of pediatric schistosomiasis in hard-to-reach areas and populations: a scoping review protocol
Journal F1000Res
Volume 11
Pages / Article-Number 1203
Keywords Child, Preschool; Child; Humans; Praziquantel/therapeutic use; *Schistosomiasis/drug therapy/epidemiology/prevention & control; *Anthelmintics/therapeutic use; Databases, Factual; Neglected Diseases; Review Literature as Topic; Meta-Analysis as Topic; Epidemiology; Hard-to-reach; Pediatric; Praziquantel; Pre-School Aged Children; Prevalence; Schistosomiasis
Mesh terms Child, Preschool; Child; Humans; Praziquantel, therapeutic use; Schistosomiasis, prevention & control; Anthelmintics, therapeutic use; Databases, Factual; Neglected Diseases; Review Literature as Topic; Meta-Analysis as Topic
Abstract Background: Schistosomiasis is a neglected tropical disease (NTD) that affects millions of people. Children are the most vulnerable group to developing overt disease. An estimated 779 million people are at risk of schistosomiasis and 50 million preschool-age children (PSAC) need treatment. PSAC are not currently targeted by national chemotherapy campaigns due to a lack of suitable pediatric formulations of praziquantel. The Pediatric Praziquantel Consortium has developed an orally dispersible praziquantel formulation (arpraziquantel) and is facilitating its adoption for schistosomiasis control by endemic countries through the ADOPT program - an implementation research program that paves the way for the large-scale delivery of the child-friendly formulation to treat schistosomiasis in preschool-aged children in endemic countries. A key challenge for comprehensive NTD control including schistosomiasis is reaching all at-risk populations, including those hard to reach. Main access barriers include geographic, social and economic conditions. Objective : This scoping literature review aims to document the epidemiology of schistosomiasis in children under 6 years of age living in hard-to-reach areas and populations. Methods : This review will adopt the five-stage scoping review process of identifying the research question, identifying relevant studies, study selection, charting data and collating, summarizing and reporting results. Electronic databases including Medline, Web of Science, Embase (Ovid), LILACS and African Journals OnLine (AJOL) will be searched for relevant articles. Two independent reviewers will screen identified articles using a two-stage approach of reviewing the title/abstract and then the full text of provisionally retained articles. Relevant literatures will be downloaded into EndNote X9 to maintain and manage citation and facilitate the overall review process. A meta-analysis will be conducted if indicated. Relevance : The results will provide insights into the burden of schistosomiasis among marginalized PSAC, aiming to produce evidence on the need for inclusion of this population when designing the expansion of preventive chemotherapy programs.
ISSN/ISBN 2046-1402 (Electronic)2046-1402 (Linking)
URL https://doi.org/10.12688/f1000research.126884.2
edoc-URL https://edoc.unibas.ch/93689/
Full Text on edoc Available
Digital Object Identifier DOI 10.12688/f1000research.126884.2
PubMed ID http://www.ncbi.nlm.nih.gov/pubmed/36761831
ISI-Number MEDLINE:36761831
Document type (ISI) Journal Article
 
   

MCSS v5.8 PRO. 0.350 sec, queries - 0.000 sec ©Universität Basel  |  Impressum   |    
15/06/2024