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A note on ethnic sensitivity studies.
| JournalArticle (Originalarbeit in einer wissenschaftlichen Zeitschrift) |
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| ID |
4662171 |
| Author(s) |
Glasbrenner, Michaela; Rosenkranz, Gerd |
| Author(s) at UniBasel |
Barbier, Michaela
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| Year |
2006 |
| Title |
A note on ethnic sensitivity studies. |
| Journal |
Journal of biopharmaceutical statistics |
| Volume |
16 |
| Number |
1 |
| Pages / Article-Number |
15-23 |
| Mesh terms |
Clinical Protocols; Clinical Trials as Topic; Dose-Response Relationship, Drug; Ethnicity; Humans; Models, Statistical; Patient Selection; Pharmacokinetics; Sample Size |
| Abstract |
In this article, we propose a similarity criterion for ethnic sensitivity studies in pharmacokinetic variables. We present how this criterion can be used in the context of different dose-exposure models and how sample size and power calculations can be done. Examples for the planning and analysis of ethnic sensitivity studies are provided. |
| ISSN/ISBN |
1054-3406 |
| Full Text on edoc |
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| Digital Object Identifier DOI |
10.1080/10543400500406454 |
| PubMed ID |
http://www.ncbi.nlm.nih.gov/pubmed/16440834 |
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