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[Polypharmacy and inappropriate medications in multimorbid elderly patients - What OPERAM taught us and will teach us].
JournalArticle (Originalarbeit in einer wissenschaftlichen Zeitschrift) |
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ID |
4658554 |
Author(s) |
Bretagne, Lisa; Tabea Jungo, Katharina; Blum, Manuel R; Schwenkglenks, Matthias; Chiolero, Arnaud; Del Giovane, Cinzia; Gencer, Baris; Aujesky, Drahomir; Rodondi, Nicolas |
Author(s) at UniBasel |
Schwenkglenks, Matthias
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Year |
2022 |
Title |
[Polypharmacy and inappropriate medications in multimorbid elderly patients - What OPERAM taught us and will teach us]. |
Journal |
Revue medicale suisse |
Volume |
18 |
Number |
772 |
Pages / Article-Number |
427-432 |
Mesh terms |
Aged; Aged, 80 and over; Humans; Inappropriate Prescribing; Multicenter Studies as Topic; Multimorbidity; Polypharmacy; Potentially Inappropriate Medication List; Quality of Life; Randomized Controlled Trials as Topic |
Abstract |
Polypharmacy and inappropriate medication use are very common in multimorbid older patients. This population has unfortunately been excluded from most large, randomized studies. In a recent multicenter randomized study (OPERAM), we included over 2000 multimorbid patients. We found that 86% of the patients aged 70 years and more had inappropriate medications and that these medications could be discontinued without negative impact on the health of these patients. This cohort of multimorbid patients will be followed for 10 years to evaluate their prognosis, life expectancy, treatments and quality of life, with numerous projects to better understand the inappropriate prescribing of individual drugs and their consequences on the health of this population. |
ISSN/ISBN |
1660-9379 |
Full Text on edoc |
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Digital Object Identifier DOI |
10.53738/REVMED.2022.18.772.427 |
PubMed ID |
http://www.ncbi.nlm.nih.gov/pubmed/35266342 |
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