It is a challenge for pharmacy universities worldwide to combine theoretical knowledge with practical skills to equip students for their future practice. Simulation - either virtual or on-site - has expanded rapidly as new technique of learning. In July 2022 and for the first time in Switzerland, a fully equipped pharmacy has been installed at the Pharmazentrum, University of Basel, for simulation purposes. Scientific research is needed to establish simulation in the curriculum. This project aims at developing scenarios from clinical / pharmaceutical cases to be used by pharmacy students in simulation. Variables for the assessment of learning progress will be determined. A comparison with digital simulation is planned.