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Development of brain-penetrant MNK inhibitors
Third-party funded project
Project title Development of brain-penetrant MNK inhibitors
Principal Investigator(s) Genç, Özgür
Lill, Markus A.
Scheiffele, Peter
Organisation / Research unit Departement Pharmazeutische Wissenschaften / Computational Pharmacy (Lill),
Departement Biozentrum / Cell Biology (Scheiffele)
Department Departement Biozentrum
Project start 01.03.2023
Probable end 30.08.2024
Status Active
Abstract

MAP-kinase interacting kinases (MNKs) are a novel target for the treatment of autism spectrum disorders. We aim to develop a brain-penetrant, small molecule inhibitor that selectively targets MNKs and alleviates the core symptoms of autism.

Financed by Innovation Promotion Agency CTI
   

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