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Treatment outcome of imported cutaneous leishmaniasis among travellers and migrants infected with; Leishmania major; and; Leishmania tropica; : a retrospective study in European centres 2013 to 2019
JournalArticle (Originalarbeit in einer wissenschaftlichen Zeitschrift)
ID
4651590
Author(s)
Glans, H.; Dotevall, L.; Van der Auwera, G.; Bart, A.; Blum, J.; Buffet, P.; Guery, R.; Gangneux, J. P.; van Henten, S.; Harms, G.; Varani, S.; Robert-Gangneux, F.; Rongisch, R.; Andersson, B.; Bradley, M.
Treatment outcome of imported cutaneous leishmaniasis among travellers and migrants infected with; Leishmania major; and; Leishmania tropica; : a retrospective study in European centres 2013 to 2019
Journal
Int J Infect Dis
Volume
122
Pages / Article-Number
375-381
Abstract
OBJECTIVES: Cutaneous leishmaniasis (CL) in Asia, Northern and Sub-Saharan Africa is mainly caused by Leishmania major and Leishmania tropica. We describe and evaluate the treatment outcome of CL among travellers and migrants in Europe. METHODS: A retrospective study of parasitological confirmed CL cases caused by L. major and L. tropica during 2013-2019 in Europe. Data were collected from medical records and databases within the LeishMan network. RESULTS: Out of 206 included cases of CL, seventy-five were identified as L. major and 131 as L. tropica. Eighty percent of the patients with L. tropica infection were migrants, whereas 53 % of patients with L. major infection had been visiting friends and relatives. Among patients with L. tropica, 48 %, were younger than 15. Pentavalent antimony cured 73 % (L. major) and 78 % (L. tropica). Intralesional administration had a cure rate, 86 % and systemic, 67%, on L. tropica. Liposomal amphotericin B had a cure rate of 44-63 %. CONCLUSION: L. major infections were mostly found in individuals visiting friends and relatives, whereas L. tropica were mainly identified in migrants. No patients with L. major relapsed. Pentavalent antimony, liposomal amphotericin B and cryotherapy had cure rates in accordance with previous studies.
