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Retrosynthetic polyketide disconnections for unnatural aromatics
JournalArticle (Originalarbeit in einer wissenschaftlichen Zeitschrift)
 
ID 4650930
Author(s) Wu, Xingxing; Sparr, Christof
Author(s) at UniBasel Sparr, Christof
Year 2022
Title Retrosynthetic polyketide disconnections for unnatural aromatics
Journal Trends in chemistry
Volume 4
Number 5
Pages / Article-Number 367-370
Abstract Polyketide synthases are extraordinarily complex enzymatic machineries that govern the assembly and cyclization of poly-β-carbonyl intermediates to an enormous diversity of natural products. Captivatingly, this biosynthetic strategy is transferable to the retrosynthetic analysis of unnatural aromatics, enabling strategic biomimetic polyketide cyclizations to design an extensive range of otherwise unrelated aromatic products.
Publisher Elsevier
ISSN/ISBN 2589-5974
edoc-URL https://edoc.unibas.ch/90229/
Full Text on edoc Available
Digital Object Identifier DOI 10.1016/j.trechm.2022.01.013
ISI-Number 000793458600002
Document type (ISI) Editorial Material
 
   

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