Data Entry: Please note that the research database will be replaced by UNIverse by the end of October 2023. Please enter your data into the system https://universe-intern.unibas.ch. Thanks
A Guide to a Pharmacist-Led Pharmacogenetic Testing and Counselling Service in an Interprofessional Healthcare Setting
JournalArticle (Originalarbeit in einer wissenschaftlichen Zeitschrift)
ID
4647348
Author(s)
Stäuble, Céline K.; Jeiziner, Chiara; Bollinger, Anna; Wiss, Florine M.; Hatzinger, Martin; Hersberger, Kurt E.; Ihde, Thomas; Lampert, Markus L.; Mikoteit, Thorsten; Meyer Zu Schwabedissen, Henriette E.; Allemann, Samuel S.
A Guide to a Pharmacist-Led Pharmacogenetic Testing and Counselling Service in an Interprofessional Healthcare Setting
Journal
Pharmacy (Basel, Switzerland)
Volume
10
Number
4
Pages / Article-Number
86
Keywords
clinical pharmacy; community pharmacy; hospital pharmacy; medication review; personalized medicine; pharmaceutical care; pharmacogenomics; pharmacy service; primary care; secondary care
Abstract
Genetic predisposition is one factor influencing interindividual drug response. Pharmacogenetic information can be used to guide the selection and dosing of certain drugs. However, the implementation of pharmacogenetics (PGx) in clinical practice remains challenging. Defining a formal structure, as well as concrete procedures and clearly defined responsibilities, may facilitate and increase the use of PGx in clinical practice. Over 140 patient cases from an observational study in Switzerland formed the basis for the design and refinement of a pharmacist-led pharmacogenetics testing and counselling service (PGx service) in an interprofessional setting. Herein, we defined a six-step approach, including: (1) patient referral; (2) pre-test-counselling; (3) PGx testing; (4) medication review; (5) counselling; (6) follow-up. The six-step approach supports the importance of an interprofessional collaboration and the role of pharmacists in PGx testing and counselling across healthcare settings.
