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Short-Term Joint Effects of PM; 10; , NO; 2; and SO; 2; on Cardio-Respiratory Disease Hospital Admissions in Cape Town, South Africa
JournalArticle (Originalarbeit in einer wissenschaftlichen Zeitschrift)
ID 4646599
Author(s) Adebayo-Ojo, Temitope Christina; Wichmann, Janine; Arowosegbe, Oluwaseyi Olalekan; Probst-Hensch, Nicole; Schindler, Christian; Künzli, Nino
Author(s) at UniBasel Adebayo, Temitope
Arowosegbe, Oluwaseyi Olalekan
Schindler, Christian
Probst-Hensch, Nicole
Künzli, Nino
Year 2022
Title Short-Term Joint Effects of PM; 10; , NO; 2; and SO; 2; on Cardio-Respiratory Disease Hospital Admissions in Cape Town, South Africa
Journal International Journal of Environmental Research and Public Health
Volume 19
Number 1
Pages / Article-Number 495
Keywords Cape Town; DLNM; South Africa; ambient air pollution; cardiovascular disease; multi pollutant; respiratory disease; short-term; time-series analysis
Mesh terms Air Pollution, analysis, statistics & numerical data; Child; Hospitals; Humans; Nitrogen Dioxide, analysis, toxicity; Respiratory Tract Diseases, epidemiology; South Africa, epidemiology
Abstract In sub-Sahara Africa, few studies have investigated the short-term association between hospital admissions and ambient air pollution. Therefore, this study explored the association between multiple air pollutants and hospital admissions in Cape Town, South Africa.; Generalized additive quasi-Poisson models were used within a distributed lag linear modelling framework to estimate the cumulative effects of PM; 10; , NO; 2; , and SO; 2; up to a lag of 21 days. We further conducted multi-pollutant models and stratified our analysis by age group, sex, and season.; The overall relative risk (95% confidence interval (CI)) for PM; 10; , NO; 2; , and SO; 2; at lag 0-1 for hospital admissions due to respiratory disease (RD) were 1.9% (0.5-3.2%), 2.3% (0.6-4%), and 1.1% (-0.2-2.4%), respectively. For cardiovascular disease (CVD), these values were 2.1% (0.6-3.5%), 1% (-0.8-2.8%), and -0.3% (-1.6-1.1%), respectively, per inter-quartile range increase of 12 µg/m; 3; for PM; 10; , 7.3 µg/m; 3; for NO; 2; , and 3.6 µg/m; 3; for SO; 2; . The overall cumulative risks for RD per IQR increase in PM; 10; and NO; 2; for children were 2% (0.2-3.9%) and 3.1% (0.7-5.6%), respectively.; We found robust associations of daily respiratory disease hospital admissions with daily PM; 10; and NO; 2; concentrations. Associations were strongest among children and warm season for RD.
Publisher MDPI
ISSN/ISBN 1661-7827 ; 1660-4601
Full Text on edoc Available
Digital Object Identifier DOI 10.3390/ijerph19010495
PubMed ID
ISI-Number WOS:000759267500001
Document type (ISI) Journal Article

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