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Clustered cardiovascular disease risk among children aged 8-13 years from lower socioeconomic schools in Gqeberha, South Africa
JournalArticle (Originalarbeit in einer wissenschaftlichen Zeitschrift)
ID 4645696
Author(s) Dolley, Danielle; Walter, Cheryl; du Randt, Rosa; Pühse, Uwe; Bosma, Jacob; Aerts, Ann; Adams, Larissa; Arnaiz, Patricia; Degen, Jan; Gall, Stefanie; Joubert, Nandi; Müller, Ivan; Nienhaber, Madeleine; Nqweniso, Felicitas; Seelig, Harald; Steinmann, Peter; Utzinger, Jürg; Gerber, Markus
Author(s) at UniBasel Pühse, Uwe
Arnaiz Jimenez, Patricia
Degen, Jan
Joubert, Nandi
Müller, Ivan
Seelig, Harald
Gerber, Markus
Steinmann, Peter
Utzinger, Jürg
Year 2022
Title Clustered cardiovascular disease risk among children aged 8-13 years from lower socioeconomic schools in Gqeberha, South Africa
Journal BMJ Open Sport & Exercise Medicine
Volume 8
Number 2
Pages / Article-Number e001336
Abstract Objectives To determine the prevalence of individual cardiovascular disease (CVD) risk factors and clustered CVD risk among children attending schools in periurban areas of Gqeberha and to investigate the independent association between clustered CVD risk, moderate to vigorous physical activity (MVPA) and cardiorespiratory fitness (CRF). Methods Baseline data were collected in a cross-sectional analysis of 975 children aged 8-13 years. We measured the height, weight, waist circumference, blood pressure, fasting glucose, full lipid panel, 20 m shuttle run performance and accelerometry. The prevalence of individual risk factors was determined, and a clustered risk score (CRS) was constructed using principal component analysis. Children with an elevated CRS of 1 SD above the average CRS were considered 'at-risk'. Results We found 424 children (43.3%) having at least one elevated CVD risk factor: 27.7% elevated triglycerides, 20.7% depressed high-density lipoprotein cholesterol and 15.9% elevated total cholesterol. An elevated clustered risk was identified in 17% (n=104) of the sample; girls exhibited a significantly higher CRS >1 SD than boys (p=0.036). The estimated odds of an elevated clustered risk are doubled every 2 mL/kg/min decrease in VO 2 max (95% CI 1.66 to 3.12) or every 49 min reduction in MVPA (95% CI 27 to 224). Conclusion A relatively high prevalence of elevated individual and clustered CVD risk was identified. Our results have also confirmed the independent inverse association of the clustered CVD risk with physical activity and CRF. These indicate that increased levels of CRF or MVPA may aid in the prevention and reduction of elevated clustered CVD risk.
Publisher BMJ Publishing Group
ISSN/ISBN 2055-7647
Full Text on edoc Available
Digital Object Identifier DOI 10.1136/bmjsem-2022-001336
PubMed ID
ISI-Number WOS:000817212800002
Document type (ISI) Journal Article

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