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Implementing 3Rs in Switzerland: an interdisciplinary in-depth exploration of barriers and facilitators [Implement-3R]
Third-party funded project
Project title Implementing 3Rs in Switzerland: an interdisciplinary in-depth exploration of barriers and facilitators [Implement-3R]
Principal Investigator(s) Elger, Bernice Simone
Co-Investigator(s) Kwak, Brenda Renata
Affolter, Markus
Blattner, Charlotte
Würbel, Hanno
Project Members Milford, Aoife
Louis-Maerten, Edwin
Shaw, David
De Clercq, Eva
Rodriguez, Christian
Organisation / Research unit Departement Biozentrum / Cell Biology (Affolter),
Ethik / Bio- und Medizinethik (Elger)
Department Ethik
Project start 01.12.2022
Probable end 30.11.2026
Status Active

The 3R principles and regulation of animal research
The use of animals in biomedical and other research presents an ethical dilemma: we do not want to lose scientific benefits, nor do we want to cause laboratory animals to suffer”. In Switzerland, the majority of animals (64%) is used in fundamental research and a minority (ca. 20%) are used for developing and testing pharmaceutical and chemical products. The 3R-strategies (“replace, reduce, refine”) are “today widely accepted by scientists as a moral obligation to treat animals humanely and if possible to use alternative methods in experiments”. The national and international regulatory framework concerning the use of animals for research stipulates adherence to the 3R principles[3-5]. In addition, Swiss law requires researchers to demonstrate a favourable harm-benefit ratio to justify animal experiments[6, 7]. There is an ongoing discussion in the fields of ethics, law and science concerning the interpretation of the 3Rs and harm-benefit analysis. Eminent ethicists have recently proposed a more elaborated, argued way how to balance social benefit and animal welfare in this context.

Keywords animal ethics
Financed by Swiss National Science Foundation (SNSF)

Cooperations ()

  ID Kreditinhaber Kooperationspartner Institution Laufzeit - von Laufzeit - bis
4662552  Elger, Bernice Simone  Schwab, Martin E., Prof. Dr.  Universität Zürich  01.10.2022  30.06.2027 
4662553  Elger, Bernice Simone  Schär, Primo Leo, prof. Dr.  University of Basel, Department of Biomedicine  01.10.2022  30.09.2027 
4662554  Elger, Bernice Simone  Krause, Karl-Heinz  Université de Genève Département de Pathologie Clinique  01.10.2022  30.09.2026 
4528248  Elger, Bernice Simone  Gaab, Jens, Prof. Dr.  Fakultät für Psychologie, Universität Basel  01.10.2022  30.06.2027 
4662555  Elger, Bernice Simone  Gassmann, Max, Prof. Dr.  Universität Zürich Vetsuisse-Fakultät  01.10.2022  30.06.2027 
4662556  Elger, Bernice Simone  Lüscher, Christian, Prof. Dr.  Université de Genève Dépt des Neurosciences Fondamentales  01.10.2022  30.06.2027 
4662557  Elger, Bernice Simone  Müller, Henning, Prof. Dr.  HES-SO Valais  01.10.2022  30.06.2027 
4662558  Elger, Bernice Simone  Angelillo-Scherrer, Prof. Dr.   Inselspital Universitätsklinik für Hämatologie  01.10.2022  30.06.2027 
4662701  Elger, Bernice Simone  Roppolo, Daniele, Dr.  Univ. of Geneva, Executive board members, Swiss 3R Competence  01.02.2023  30.06.2027 
4662703  Elger, Bernice Simone  Kleist, Peter, Dr.  KEK, Zürich  01.10.2022  30.06.2027 
4662704  Elger, Bernice Simone  Klenke, Elisabeth, Dr.  Deputy Head, Swissmedic  01.10.2022  30.06.2027 
4662705  Elger, Bernice Simone  Stucki, Saskia, Dr. iur.   Aminal law, MPI, Heidelberg  01.10.2022  30.06.2027 
4662706  Elger, Bernice Simone  Gordijn, Bert, Prof. Dr.   Director of the Institute of Ethics, Dublin City University, Ireland  01.10.2022  30.06.2027 
4662707  Elger, Bernice Simone  Vinken, Mathieu, Prof. Dr.   Vrije University Brussels  01.10.2022  30.06.2027 
4662551  Elger, Bernice Simone  Hugues, Stéphanie, Prof. Dr.  Faculté de Médecine / CMU  01.10.2022  30.09.2027 

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