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Implementing 3Rs in Switzerland: an interdisciplinary in-depth exploration of barriers and facilitators [Implement-3R]
Third-party funded project |
Project title |
Implementing 3Rs in Switzerland: an interdisciplinary in-depth exploration of barriers and facilitators [Implement-3R] |
Principal Investigator(s) |
Elger, Bernice Simone
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Co-Investigator(s) |
Kwak, Brenda Renata Affolter, Markus Blattner, Charlotte Würbel, Hanno
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Project Members |
Milford, Aoife Louis-Maerten, Edwin Shaw, David De Clercq, Eva Rodriguez, Christian
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Organisation / Research unit |
Departement Biozentrum / Cell Biology (Affolter), Ethik / Bio- und Medizinethik (Elger) |
Department |
Ethik |
Project start |
01.12.2022 |
Probable end |
30.11.2026 |
Status |
Active |
Abstract |
The 3R principles and regulation of animal research The use of animals in biomedical and other research presents an ethical dilemma: we do not want to lose scientific benefits, nor do we want to cause laboratory animals to suffer”. In Switzerland, the majority of animals (64%) is used in fundamental research and a minority (ca. 20%) are used for developing and testing pharmaceutical and chemical products. The 3R-strategies (“replace, reduce, refine”) are “today widely accepted by scientists as a moral obligation to treat animals humanely and if possible to use alternative methods in experiments”. The national and international regulatory framework concerning the use of animals for research stipulates adherence to the 3R principles[3-5]. In addition, Swiss law requires researchers to demonstrate a favourable harm-benefit ratio to justify animal experiments[6, 7]. There is an ongoing discussion in the fields of ethics, law and science concerning the interpretation of the 3Rs and harm-benefit analysis. Eminent ethicists have recently proposed a more elaborated, argued way how to balance social benefit and animal welfare in this context. |
Keywords |
animal ethics |
Financed by |
Swiss National Science Foundation (SNSF)
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Cooperations () |
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ID |
Kreditinhaber |
Kooperationspartner |
Institution |
Laufzeit - von |
Laufzeit - bis |
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4662552 |
Elger, Bernice Simone |
Schwab, Martin E., Prof. Dr. |
Universität Zürich |
01.10.2022 |
30.06.2027 |
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4662553 |
Elger, Bernice Simone |
Schär, Primo Leo, prof. Dr. |
University of Basel, Department of Biomedicine |
01.10.2022 |
30.09.2027 |
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4662554 |
Elger, Bernice Simone |
Krause, Karl-Heinz |
Université de Genève Département de Pathologie Clinique |
01.10.2022 |
30.09.2026 |
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4528248 |
Elger, Bernice Simone |
Gaab, Jens, Prof. Dr. |
Fakultät für Psychologie, Universität Basel |
01.10.2022 |
30.06.2027 |
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4662555 |
Elger, Bernice Simone |
Gassmann, Max, Prof. Dr. |
Universität Zürich Vetsuisse-Fakultät |
01.10.2022 |
30.06.2027 |
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4662556 |
Elger, Bernice Simone |
Lüscher, Christian, Prof. Dr. |
Université de Genève Dépt des Neurosciences Fondamentales |
01.10.2022 |
30.06.2027 |
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4662557 |
Elger, Bernice Simone |
Müller, Henning, Prof. Dr. |
HES-SO Valais |
01.10.2022 |
30.06.2027 |
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4662558 |
Elger, Bernice Simone |
Angelillo-Scherrer, Prof. Dr. |
Inselspital Universitätsklinik für Hämatologie |
01.10.2022 |
30.06.2027 |
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4662701 |
Elger, Bernice Simone |
Roppolo, Daniele, Dr. |
Univ. of Geneva, Executive board members, Swiss 3R Competence |
01.02.2023 |
30.06.2027 |
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4662703 |
Elger, Bernice Simone |
Kleist, Peter, Dr. |
KEK, Zürich |
01.10.2022 |
30.06.2027 |
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4662704 |
Elger, Bernice Simone |
Klenke, Elisabeth, Dr. |
Deputy Head, Swissmedic |
01.10.2022 |
30.06.2027 |
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4662705 |
Elger, Bernice Simone |
Stucki, Saskia, Dr. iur. |
Aminal law, MPI, Heidelberg |
01.10.2022 |
30.06.2027 |
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4662706 |
Elger, Bernice Simone |
Gordijn, Bert, Prof. Dr. |
Director of the Institute of Ethics, Dublin City University, Ireland |
01.10.2022 |
30.06.2027 |
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4662707 |
Elger, Bernice Simone |
Vinken, Mathieu, Prof. Dr. |
Vrije University Brussels |
01.10.2022 |
30.06.2027 |
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4662551 |
Elger, Bernice Simone |
Hugues, Stéphanie, Prof. Dr. |
Faculté de Médecine / CMU |
01.10.2022 |
30.09.2027 |
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