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Detection and resolution of drug-related problems at hospital discharge focusing on information availability - a retrospective analysis.
JournalArticle (Originalarbeit in einer wissenschaftlichen Zeitschrift)
ID 4636131
Author(s) Imfeld-Isenegger, Tamara L; Studer, Helene; Ceppi, Marco G; Rosen, Christoph; Bodmer, Michael; Beeler, Patrick E; Boeni, Fabienne; Häring, Armella P; Hersberger, Kurt E; Lampert, Markus L
Author(s) at UniBasel Hersberger, Kurt
Studer, Helene Marlene
Ceppi, Marco Giacomo
Rosen, Christoph
Bodmer, Michael
Beeler, Patrick
Böni, Fabienne
Häring, Armelle
Lampert, Markus Leopold
Year 2021
Title Detection and resolution of drug-related problems at hospital discharge focusing on information availability - a retrospective analysis.
Journal Zeitschrift fur Evidenz, Fortbildung und Qualitat im Gesundheitswesen
Volume 166
Pages / Article-Number 18-26
Keywords Arzneimittelbezogene Probleme; Community pharmacy; Drug-related problems; Hospital discharge; Information availability; Informationszugang; Medication reconciliation; Medication review; Medikationsabgleich; Medikationsanalyse; Spitalaustritt; Öffentliche Apotheke
Mesh terms Cohort Studies; Drug-Related Side Effects and Adverse Reactions; Germany; Hospitals; Humans; Medication Reconciliation; Patient Discharge; Pharmaceutical Preparations; Retrospective Studies

Hospital stays are often associated with medication changes, which may lead to drug-related problems (DRPs). Medication reconciliation and medication reviews are strategies to detect and resolve DRPs.; A descriptive cohort study was conducted using DRPs collected during routine pharmacist-led medication reconciliation and medication reviews in the hospital's community pharmacy at discharge (Zug Cantonal Hospital, Switzerland). In a simulation experiment, we retrospectively analysed the detection and resolution possibilities of these DRPs and their dependency on different information sources.; Overall, 6,087 prescriptions were filled in the hospital's community pharmacy (between June 2016 and May 2019). Among 1,352 prescriptions (with ≥ 1 documented DRP) a total of 1,876 DRPs were detected. The retrospective assessment showed that 1,115 DRPs could have been detected by performing simple medication reviews (based on the discharge prescription and the medication history), whereas in the remaining cases, additional clinical and/or patient-specific information would have been needed. In 944 (84.7 %) DRPs, which are detectable by simple medication reviews, the pharmacist would need to consult the prescriber for resolution.; The detection of DRPs is strongly influenced by the information available. These results support models with pre-discharge medication reconciliation and pharmacist-led medication review procedures enabling both comprehensive detection and facilitated resolution of DRPs.

ISSN/ISBN 2212-0289
Full Text on edoc
Digital Object Identifier DOI 10.1016/j.zefq.2021.08.004
PubMed ID

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