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A Close-to-Aromatize Approach for the Late-Stage Functionalization through Ring Closing Metathesis
JournalArticle (Originalarbeit in einer wissenschaftlichen Zeitschrift)
 
ID 4619895
Author(s) Lozhkin, Boris; Ward, Thomas R.
Author(s) at UniBasel Ward, Thomas R.
Year 2021
Title A Close-to-Aromatize Approach for the Late-Stage Functionalization through Ring Closing Metathesis
Journal Helvetica Chimica Acta
Volume 104
Number 5
Pages / Article-Number e2100024
Keywords elimination; late-stage functionalization; metathesis; ring closing metathesis
Abstract An efficient approach for the synthesis of monosubstituted aromatic compounds relying on a ring-closing metathesis followed by spontaneous 1,2-elimination is presented. The efficiency for late-stage functionalization is highlighted in various solvents (up to 920 TON). This approach is compatible with strained cycles and other multiple bonds in the substrate.
Publisher Wiley
ISSN/ISBN 0018-019X ; 1522-2675
edoc-URL https://edoc.unibas.ch/83131/
Full Text on edoc Available
Digital Object Identifier DOI 10.1002/hlca.202100024
ISI-Number 000647234200001
Document type (ISI) Article
 
   

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29/03/2024