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Multi-modal diffeomorphic demons registration based on point-wise mutual information
Book title (Conference Proceedings)
IEEE International Symposium on Biomedical Imaging: From Nano to Macro
Place of Conference
Rotterdam, Netherlands
Publisher
IEEE
Pages
372-375
ISSN/ISBN
1945-7928 ; 1945-8452 ; 978-1-4244-4125-9
Abstract
In this paper we propose a variational approach for multimodal image registration based on the diffeomorphic demons algorithm. Diffeomorphic demons has proven to be a robust and efficient way for intensity-based image registration. However, the main drawback is that it cannot deal with multiple modalities. We propose to replace the standard demons similarity metric (image intensity differences) by point-wise mutual information (PMI) in the energy function. By comparing the accuracy between our PMI based diffeomorphic demons and the B-Spline based free-form deformation approach (FFD) on simulated deformations, we show the proposed algorithm performs significantly better.
