A study on the epidemiology of tinnitus in the United Kingdom
JournalArticle (Originalarbeit in einer wissenschaftlichen Zeitschrift)
ID 4525414
Author(s) Stohler, Nadja A.; Reinau, Daphne; Jick, Susan S.; Bodmer, Daniel; Meier, Christoph R.
Author(s) at UniBasel Meier, Christoph R.
Year 2019
Title A study on the epidemiology of tinnitus in the United Kingdom
Journal Clinical epidemiology
Volume 11
Pages / Article-Number 855-871
Keywords case-control study; clinical practice research datalink; incidence rates; lifestyle factors; tinnitus
Abstract Subjective tinnitus is a common symptom with potentially negative impact on quality of life. More research is required to gain a deeper understanding of the disease and its clinical presentation. To estimate the incidence of tinnitus and to describe patient-related characteristics such as lifestyle factors and comorbidities.; Using the Clinical Practice Research Datalink, we calculated incidence rates of first-time diagnosed tinnitus in an adult population between 2000 and 2016. We stratified incidence rates by sex, age, and year of diagnosis. Additionally, we performed a 1:1 matched case-control study comparing body mass index, lifestyle factors and selected comorbidities between patients with incident tinnitus and tinnitus-free controls.; We identified 109 783 adults with a first-time diagnosis of tinnitus between 2000 and 2016, yielding an overall age-standardized incidence rate of 25.0 new tinnitus cases per 10,000 person-years (95% CI: 24.6-25.5). There was a steady increase in tinnitus incidence throughout the study period. Approximately 80% of tinnitus cases were diagnosed at age 40 years or older. We observed the highest incidence rate in individuals aged 60-69 years (41.2 per 10,000 person-years, 95% CI: 40.7-41.7). Smokers and alcohol drinkers were at lower risk of being diagnosed with tinnitus compared with non-smokers and non-drinkers, respectively. The occurrence of tinnitus was strongly associated with a recent diagnosis of several otological and vestibular disorders as well as head and neck disorders.; The present observational study found an increasing incidence of tinnitus over time, emphasizing the continuously growing health burden. The findings on patient characteristics, lifestyle factors, and selected comorbidities contribute to a better understanding of risk factors for tinnitus.
Publisher Dove medical press
ISSN/ISBN 1179-1349
URL https://doi.org/10.2147/CLEP.S213136
edoc-URL https://edoc.unibas.ch/74301/
Full Text on edoc No
Digital Object Identifier DOI 10.2147/CLEP.S213136
PubMed ID http://www.ncbi.nlm.nih.gov/pubmed/31572016
ISI-Number WOS:000485908700001
Document type (ISI) Article

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