1,4-Palladium Shift/C(sp(3))-H Activation Strategy for the Remote Construction of Five-Membered Rings

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1,4-Palladium Shift/C(sp(3))-H Activation Strategy for the Remote Construction of Five-Membered Rings

JournalArticle (Originalarbeit in einer wissenschaftlichen Zeitschrift)

ID	4501581
Author(s)	Rocaboy, Ronan; Baudoin, Olivier
Author(s) at UniBasel	Baudoin, Olivier
Year	2019
Title	1,4-Palladium Shift/C(sp(3))-H Activation Strategy for the Remote Construction of Five-Membered Rings
Journal	Organic Letters
Volume	21
Number	5
Pages / Article-Number	1434-1437
Abstract	1,n-Metal shift is an elegant alternative approach enabling the functionalization of remote C H bonds from simple precursors. In this work, we report a novel and simple Pd-0-catalyzed domino reaction involving 1,4-palladium shift and C(sp(3))-H activation and leading to (fused) five-membered rings. This method allowed access to a broad range of valuable arylidene gamma-lactams and indanones and was applied to the formal synthesis of (-)-pyrrolam.
Publisher	American Chemical Society
ISSN/ISBN	1523-7060 ; 1523-7052
edoc-URL	https://edoc.unibas.ch/71338/
Full Text on edoc	Restricted
Digital Object Identifier DOI	10.1021/acs.orglett.9b00187
PubMed ID	http://www.ncbi.nlm.nih.gov/pubmed/30735399
ISI-Number	000460491700041
Document type (ISI)	Article

19/04/2024

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