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Terpenoids and phenolics of Micromeria persica
JournalArticle (Originalarbeit in einer wissenschaftlichen Zeitschrift)
 
ID 4500789
Author(s) Kalaki Kordkolaei, Sakineh; Kanani, Mohammad Reza; Tabefam, Marzieh; Sarvestani, Nazanin Namazi; Hamburger, Matthias; Moridi Farimani, Mahdi
Author(s) at UniBasel Hamburger, Matthias
Year 2020
Title Terpenoids and phenolics of Micromeria persica
Journal Natural Product Research
Volume 34
Number 20
Pages / Article-Number 2913-2918
Mesh terms Antineoplastic Agents, Phytogenic, pharmacology; Cell Line, Tumor; Flavonoids, isolation & purification; Humans; Inhibitory Concentration 50; Lamiaceae, chemistry; Molecular Structure; Phenols, isolation & purification; Terpenes, isolation & purification; Triterpenes, isolation & purification
Abstract Phytochemical investigation of the aerial parts of Micromeria persica led to the isolation of a new oleane type triterpenoid ester (1), together with six known compounds 2–7), comprising one phenyl ethanoid ester, one glycosylated flavonoid, two triterpenoids, and two steroids. Their structures were elucidated by interpretation of their one-dimensional and two-dimensional NMR spectra and completed by the analysis of the HRESIMS data. Compounds 1 and 3 were evaluated for their cytotoxic feature against human breast adenocarcinoma cell line (MDA-MB231) and human prostate cancer cell line (DU145). However, they did not show positive effect (IC50 > 75µM).
Publisher Taylor & Francis
ISSN/ISBN 1478-6419 ; 1478-6427
edoc-URL https://edoc.unibas.ch/70827/
Full Text on edoc No
Digital Object Identifier DOI 10.1080/14786419.2019.1598988
PubMed ID http://www.ncbi.nlm.nih.gov/pubmed/30990075
ISI-Number WOS:000466064200001
Document type (ISI) Journal Article
 
   

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03/05/2024