Logo der Universität Basel

Research Database / FORSCHUNGSDATENBANK 
PRINTDOC
 
Publication 4496199 | Verified
 

Data Entry: Please note that the research database will be replaced by UNIverse by the end of October 2023. Please enter your data into the system https://universe-intern.unibas.ch. Thanks

Login for users with Unibas email account...

Login for registered users without Unibas email account...

 
An artificial metalloenzyme for carbene transfer based on a biotinylated dirhodium anchored within streptavidin
JournalArticle (Originalarbeit in einer wissenschaftlichen Zeitschrift)
 
ID 4496199
Author(s) Zhao, Jingming; Bachmann, Daniel G.; Lenz, Markus; Gillingham, Dennis G.; Ward, Thomas R.
Author(s) at UniBasel Ward, Thomas R.
Zhao, Jingming
Gillingham, Dennis
Bachmann, Daniel
Year 2018
Title An artificial metalloenzyme for carbene transfer based on a biotinylated dirhodium anchored within streptavidin
Journal Catalysis science & technology
Volume 8
Number 9
Pages / Article-Number 2294-2298
Abstract We report on artificial metalloenzymes that incorporate a biotinylated dirhodium core embedded within engineered streptavidin (Sav hereafter) variants. The resulting biohybrid catalyzes the carbene insertion in C-H bonds and olefins. Chemical- and genetic optimization allows to modulate the catalytic activity of the artificial metalloenzymes that are shown to be active in the periplasm of E. coli (up to 20 turnovers).
Publisher Royal Society of Chemistry
ISSN/ISBN 2044-4753 ; 2044-4761
edoc-URL https://edoc.unibas.ch/68780/
Full Text on edoc Available
Digital Object Identifier DOI 10.1039/c8cy00646f
ISI-Number 000433163900004
Document type (ISI) Article
 
   

MCSS v5.8 PRO. 0.358 sec, queries - 0.000 sec ©Universität Basel  |  Impressum   |    
23/04/2024