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"In vitro" Testung des Potentials endokriner Aktivität von Druckfarbstoffen
Third-party funded project |
Project title |
"In vitro" Testung des Potentials endokriner Aktivität von Druckfarbstoffen |
Principal Investigator(s) |
Odermatt, Alex
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Co-Investigator(s) |
Smiesko, Martin
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Organisation / Research unit |
Departement Pharmazeutische Wissenschaften, Departement Pharmazeutische Wissenschaften / Molecular and Systems Toxicology (Odermatt) |
Project start |
01.10.2018 |
Probable end |
30.06.2019 |
Status |
Completed |
Abstract |
A total of 20 food ink chemicals will be tested for potential interferences with the activities of several steroid hormone receptors, including estrogen-, androgen-, progesterone-, mineralocorticoid-, and glucocorticoid receptor. Both agonist and antagonist mode will be assessed. The compounds were selected based on in silico predictions using the Virtual Tox-Lab. |
Keywords |
endocrine disruptors, steroid hormone, steroid receptor |
Financed by |
Swiss Government (Research Cooperations) Foundations and Associations
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25/04/2024
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