"In vitro" Testung des Potentials endokriner Aktivität von Druckfarbstoffen
Third-party funded project
Project title "In vitro" Testung des Potentials endokriner Aktivität von Druckfarbstoffen
Principal Investigator(s) Odermatt, Alex
Co-Investigator(s) Smiesko, Martin
Organisation / Research unit Departement Pharmazeutische Wissenschaften,
Departement Pharmazeutische Wissenschaften / Molecular and Systems Toxicology (Odermatt)
Project start 01.10.2018
Probable end 30.06.2019
Status Completed
Abstract

A total of 20 food ink chemicals will be tested for potential interferences with the activities of several steroid hormone receptors, including estrogen-, androgen-, progesterone-, mineralocorticoid-, and glucocorticoid receptor. Both agonist and antagonist mode will be assessed. The compounds were selected based on in silico predictions using the Virtual Tox-Lab.

Keywords endocrine disruptors, steroid hormone, steroid receptor
Financed by Swiss Government (Research Cooperations)
Foundations and Associations
   

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