The Obesity Factor: How Cardiorespiratory Fitness is Estimated More Accurately in People with Obesity
JournalArticle (Originalarbeit in einer wissenschaftlichen Zeitschrift)
ID 4479524
Author(s) Königstein, Karsten; Klenk, Christopher; Rossmeissl, Anja; Baumann, Sandra; Infanger, Denis; Hafner, Benjamin; Hinrichs, Timo; Hanssen, Henner; Schmidt-Trucksäss, Arno
Author(s) at UniBasel Hinrichs, Timo
Königstein, Karsten
Klenk, Christopher
Rossmeissl, Anja
Baumann, Sandra
Infanger, Denis
Hafner, Benjamin
Hanssen, Henner
Schmidt-Trucksäss, Arno
Year 2018
Title The Obesity Factor: How Cardiorespiratory Fitness is Estimated More Accurately in People with Obesity
Journal Obesity (Silver Spring, Md.)
Volume 26
Number 2
Pages / Article-Number 291-298
Abstract Cardiopulmonary exercise testing is clinically used to estimate cardiorespiratory fitness (CRF). The relation to total body mass (TBM) leads to an underestimation of CRF in people with obesity and to inappropriate prognostic and therapeutic decisions. This study aimed to determine body composition-derived bias in the estimation of CRF in people with obesity.; Two hundred eleven participants (58.8% women; mean BMI 35.7 kg/m; 2; [± 6.94; 20.7-58.6]) were clinically examined, and body composition (InBody720; InBody Co., Ltd., Seoul, South Korea) and spiroergometrical peak oxygen consumption (VO; 2; peak) were assessed. The impacts of TBM, lean body mass (LBM), and skeletal muscle mass (SMM) on CRF estimates were analyzed by the application of respective weight models. Linear regression and plotting of residuals against BMI were performed on the whole study population and two subgroups (BMI < 30 kg/m; 2; and BMI ≥ 30 kg/m; 2; ).; For every weight model, Δmean VO; 2; peak (expected - measured) was positive. LBM and SMM had a considerable impact on VO; 2; peak demand (P = 0.001; ΔR; 2; = 2.3%; adjusted R; 2; = 56% and P = 0.001; ΔR; 2; = 2.7%; adjusted R; 2; = 56%), whereas TBM did not. Confounding of body composition on VO; 2; peak did not differ in LBM and SMM.; TBM-adjusted overestimation of relative VO; 2; demand is much higher in people with obesity than in those without. LBM or SMM adjustment may be superior alternatives, although small residual body composition-derived bias remains.
Publisher WILEY
ISSN/ISBN 1930-739X
Full Text on edoc No
Digital Object Identifier DOI 10.1002/oby.22078
PubMed ID
ISI-Number WOS:000423227000009
Document type (ISI) Article

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