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Matrix-assisted laser desorption/ionization time of flight mass-spectrometry (MALDI-TOF MS) based typing of extended-spectrum beta-lactamase producing E. coli--a novel tool for real-time outbreak investigation
JournalArticle (Originalarbeit in einer wissenschaftlichen Zeitschrift)
ID
4379020
Author(s)
Egli, Adrian; Tschudin-Sutter, Sarah; Oberle, Michael; Goldenberger, Daniel; Frei, Reno; Widmer, Andreas F.
Matrix-assisted laser desorption/ionization time of flight mass-spectrometry (MALDI-TOF MS) based typing of extended-spectrum beta-lactamase producing E. coli--a novel tool for real-time outbreak investigation
Epidemiologically linked clusters are confirmed by typing strains with molecular typing such as pulsed-field gel electrophoresis (PFGE). We compared six extended-spectrum beta-lactamase producing E. coli of a PFGE-related cluster with Matrix-assisted laser desorption/ionization-time of flight mass-spectrometry based typing that confirmed relatedness faster and more cost-effective, but as reliable as PFGE.
