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Classification of drug-related problems with new prescriptions using a modified PCNE classification system
JournalArticle (Originalarbeit in einer wissenschaftlichen Zeitschrift)
ID 433268
Author(s) Eichenberger, Patrick M.; Lampert, Markus L.; Kahmann, Irene Vogel; van Mil, J. W. Foppe; Hersberger, Kurt E.
Author(s) at UniBasel Hersberger, Kurt
Eichenberger, Patrick
Lampert, Markus Leopold
Year 2010
Title Classification of drug-related problems with new prescriptions using a modified PCNE classification system
Journal Pharmacy world & science
Volume 32
Number 3
Pages / Article-Number 362-72
Mesh terms Adolescent; Adult; Aged; Aged, 80 and over; Community Pharmacy Services, standards; Drug Prescriptions, classification; Drug-Related Side Effects and Adverse Reactions, classification; Female; Humans; Male; Middle Aged; Pharmacists, standards; Prospective Studies; Switzerland; Young Adult
Abstract To explore and classify drug-related problems (DRPs) with new prescriptions detected in community pharmacies using a modified PCNE (Pharmaceutical Care Network Europe) classification system.; Sixty-four Swiss community pharmacies offering internships for pharmacy students.; Occurrence, nature and pharmacist's management of DRPs.; Fifth-year pharmacy students collected consecutively hospital discharge and primary care prescriptions. After training, they documented clinical and technical DRPs, causes and interventions.; Prescriptions of 616 patients (43.0% discharged from hospital) were analysed. The patients' median age was 56 years and they received a median of 3 (range 2-19) different drugs. In 121 (19.6%) prescriptions 141 clinical DRPs were detected. The most frequent clinical DRPs were potential drug-drug interactions (DDIs) (37.6%), drug choice (24.8%) and drug use problems (15.6%). These clinical DRPs led to a total of 299 interventions. There were 222 prescriptions (36.0%) that showed 278 technical DRPs, resulting in a total of 417 interventions. Most frequent technical DRPs were missing or unclear package size or therapy duration (32.7%) and missing or unclear dosing/application instructions (30.9%). Most DRPs (75.4%) could be managed by the pharmacist alone. The number of prescribed drugs was the main factor with an influence on the frequency of clinical and technical DRPs.; Clinical and technical DRPs are frequently observed in primary care as well as in hospital discharge prescriptions. The modified PCNE classification system, especially the amendment with a technical DRP category, proved to be useful and allowed the classification of all DRPs. Neither the setting (hospital discharge vs. primary care) nor the quality of electronically printed prescriptions, but only the number of prescribed drugs influenced the occurrence of clinical or technical DRPs.
Publisher KNMP
ISSN/ISBN 0928-1231
Full Text on edoc No
Digital Object Identifier DOI 10.1007/s11096-010-9377-x
PubMed ID
ISI-Number WOS:000281758900011
Document type (ISI) Journal Article

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