The ethics of health care delivery in a pediatric malaria vaccine trial: the perspectives of stakeholders from Ghana and Tanzania
JournalArticle (Originalarbeit in einer wissenschaftlichen Zeitschrift)
 
ID 4249017
Author(s) Ward, Claire Leonie; Shaw, David; Anane-Sarpong, Evelyn; Sankoh, Osman; Tanner, Marcel; Elger, Bernice
Author(s) at UniBasel Ward, Claire Leonie
Shaw, David
Elger, Bernice Simone
Anane-Sarpong, Evelyn
Tanner, Marcel
Year 2018
Title The ethics of health care delivery in a pediatric malaria vaccine trial: the perspectives of stakeholders from Ghana and Tanzania
Journal Journal of Empirical Research on Human Research Ethics
Volume 13
Number 1
Pages / Article-Number 26-41
Abstract This study explores ethical issues raised in providing medical care to participants and communities of low-resource settings involved in a Phase II/III pediatric malaria vaccine trial (PMVT). We conducted 52 key informant interviews with major stakeholders of an international multi-center PMVT (GSK/PATH-MVI RTS,S) (NCT00866619) in Ghana and Tanzania. Based on their stakeholder experiences, the responses fell into three main themes: (a) undue inducement, (b) community disparities, and (c) broad therapeutic misconceptions. The study identified the critical ethical aspects, from the perspectives of stakeholders, of delivering health care during a PMVT. The study showed that integrating research into health care services needs to be addressed in a manner that upholds the favorable risk-benefit ratio of research and attends to the health needs of local populations. The implementation of research should aim to improve local standards of care through building a collaborative agenda with local institutions and systems of health.
Publisher SAGE
ISSN/ISBN 1556-2646 ; 1556-2654
edoc-URL https://edoc.unibas.ch/59412/
Full Text on edoc No
Digital Object Identifier DOI 10.1177/1556264617742236
PubMed ID http://www.ncbi.nlm.nih.gov/pubmed/29179625
ISI-Number WOS:000419949500004
Document type (ISI) Article
 
   

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