Data Entry: Please note that the research database will be replaced by UNIverse by the end of October 2023. Please enter your data into the system https://universe-intern.unibas.ch. Thanks
Picture free recall performance linked to the brain's structural connectome
Journal
Brain and Behavior
Volume
7
Number
7
Pages / Article-Number
e00721
Abstract
Memory functions are highly variable between healthy humans. The neural correlates of this variability remain largely unknown.; Here, we investigated how differences in free recall performance are associated with DTI-based properties of the brain's structural connectome and with grey matter volumes in 664 healthy young individuals tested in the same MR scanner.; Global structural connectivity, but not overall or regional grey matter volumes, positively correlated with recall performance. Moreover, a set of 22 inter-regional connections, including some with no previously reported relation to human memory, such as the connection between the temporal pole and the nucleus accumbens, explained 7.8% of phenotypic variance.; In conclusion, this large-scale study indicates that individual memory performance is associated with the level of structural brain connectivity.
