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Upregulation of an Artificial Zymogen by Proteolysis
Journal
Angewandte Chemie International Edition
Volume
55
Number
38
Pages / Article-Number
11587-11590
Abstract
Regulation of enzymatic activity is vital to living organisms. Here, we report the development and the genetic optimization of an artificial zymogen requiring the action of a natural protease to upregulate its latent asymmetric transfer hydrogenase activity.
