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Asthma, COPD and overlap syndrome : a longitudinal study in young European adults
Journal
The European respiratory journal
Volume
46
Number
3
Pages / Article-Number
671-679
Mesh terms
Adult; Age Distribution; Asthma, therapy; Europe, epidemiology; Female; Humans; Logistic Models; Longitudinal Studies; Male; Multivariate Analysis; Prevalence; Pulmonary Disease, Chronic Obstructive, therapy; Recurrence; Respiratory Function Tests; Risk Assessment; Sex Distribution; Spirometry; Survival Rate; Syndrome; Vital Capacity, physiology; Young Adult
Abstract
We compared risk factors and clinical characteristics, 9-year lung function change and hospitalisation risk across subjects with the asthma-chronic obstructive pulmonary disease (COPD) overlap syndrome (ACOS), asthma or COPD alone, or none of these diseases.Participants in the European Community Respiratory Health Survey in 1991-1993 (aged 20-44 years) and 1999-2001 were included. Chronic airflow obstruction was defined as pre-bronchodilator forced expiratory volume in 1 s (FEV1)/forced vital capacity