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Determination of risk factors for drug-related problems: a multidisciplinary triangulation process
JournalArticle (Originalarbeit in einer wissenschaftlichen Zeitschrift)
ID 3392276
Author(s) Kaufmann, Carole P.; Stämpfli, Dominik; Hersberger, Kurt E.; Lampert, Markus L.
Author(s) at UniBasel Hersberger, Kurt
Year 2015
Title Determination of risk factors for drug-related problems: a multidisciplinary triangulation process
Journal BMJ Open
Volume 5
Number 3
Pages / Article-Number e006376
Abstract Drug-related problems (DRPs) constitute a frequent safety issue among hospitalised patients leading to patient harm and increased healthcare costs. Because many DRPs are preventable, the specific risk factors that facilitate their occurrence are of considerable interest. The objective of our study was to assess risk factors for the occurrence of DRPs with the intention to identify patients at risk for DRPs to guide and target preventive measures where they are needed most in patients.; Triangulation process using a mixed methods approach.; We conducted an expert panel, using the nominal group technique (NGT) and a qualitative analysis, to gather risk factors for DRPs. The expert panel consisted of two consultant hospital physicians (internal medicine and geriatrics), one emergency physician, one independent general practitioner, one clinical pharmacologist, one clinical pharmacist, one registered nurse, one home care nurse and two independent community pharmacists. The literature was searched for additional risk factors. Gathered factors from the literature search and the NGT were assembled and validated in a two-round Delphi questionnaire.; The NGT resulted in the identification of 33 items with 13 additional risk factors from the qualitative analysis of the discussion. The literature search delivered another 39 risk factors. The 85 risk factors were refined to produce 42 statements for the Delphi online questionnaire. Of these, 27 risk factors were judged to be 'important' or 'rather important'.; The gathered risk factors may help to characterise and identify patients at risk for DRPs and may enable clinical pharmacists to guide and target preventive measures in order to limit the occurrence of DRPs. As a further step, these risk factors will serve as the basis for a screening tool to identify patients at risk for DRPs.
Publisher BMJ Publishing
ISSN/ISBN 2044-6055
Full Text on edoc No
Digital Object Identifier DOI 10.1136/bmjopen-2014-006376
PubMed ID
ISI-Number WOS:000363458200028
Document type (ISI) Journal Article

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