Ancestral duplications and highly dynamic opsin gene evolution in percomorph fishes
JournalArticle (Originalarbeit in einer wissenschaftlichen Zeitschrift)
 
ID 3380054
Author(s) Cortesi, Fabio; Musilová, Zuzana; Stieb, Sara M; Hart, Nathan S; Siebeck, Ulrike E; Malmstrøm, Martin; Tørresen, Ole K; Jentoft, Sissel; Cheney, Karen L; Marshall, N Justin; Carleton, Karen L; Salzburger, Walter
Author(s) at UniBasel Salzburger, Walter
Year 2015
Title Ancestral duplications and highly dynamic opsin gene evolution in percomorph fishes
Journal Proceedings of the National Academy of Sciences of the United States of America
Volume 112
Number 5
Pages / Article-Number 1493-8
Keywords gene duplication, gene conversion, gene resurrection, Percomorpha, SWS2
Abstract Single-gene and whole-genome duplications are important evolutionary mechanisms that contribute to biological diversification by launching new genetic raw material. For example, the evolution of animal vision is tightly linked to the expansion of the opsin gene family encoding light-absorbing visual pigments. In teleost fishes, the most species-rich vertebrate group, opsins are particularly diverse and key to the successful colonization of habitats ranging from the bioluminescence-biased but basically dark deep sea to clear mountain streams. In this study, we report a previously unnoticed duplication of the violet-blue short wavelength-sensitive 2 (SWS2) opsin, which coincides with the radiation of highly diverse percomorph fishes, permitting us to reinterpret the evolution of this gene family. The inspection of close to 100 fish genomes revealed that, triggered by frequent gene conversion between duplicates, the evolutionary history of SWS2 is rather complex and difficult to predict. Coincidentally, we also report potential cases of gene resurrection in vertebrate opsins, whereby pseudogenized genes were found to convert with their functional paralogs. We then identify multiple novel amino acid substitutions that are likely to have contributed to the adaptive differentiation between SWS2 copies. Finally, using the dusky dottyback Pseudochromis fuscus, we show that the newly discovered SWS2A duplicates can contribute to visual adaptation in two ways: by gaining sensitivities to different wavelengths of light and by being differentially expressed between ontogenetic stages. Thus, our study highlights the importance of comparative approaches in gaining a comprehensive view of the dynamics underlying gene family evolution and ultimately, animal diversification.
Publisher National Academy of Sciences
ISSN/ISBN 0027-8424 ; 1091-6490
edoc-URL http://edoc.unibas.ch/40772/
Full Text on edoc No
Digital Object Identifier DOI 10.1073/pnas.1417803112
PubMed ID http://www.ncbi.nlm.nih.gov/pubmed/25548152
ISI-Number WOS:000349087700066
Document type (ISI) Journal Article
 
   

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