PolarNet
Third-party funded project
Project title PolarNet
Principal Investigator(s) Spang, Anne
Organisation / Research unit Departement Biozentrum / Biochemistry (Spang)
Project Website http://polarnet-itn.eu/contact/
Project start 01.10.2015
Probable end 30.09.2019
Status Completed
Abstract

The ability of cells to polarize underlies the most basic biological functions such as motility and response to external challenges, but also the formation and maintenance of tissues in a multicellular organism. The importance of cell polarity is underscored by the fact that cell polarity is essential for animal development and is perturbed in disease states such as cancer. Understanding cell polarity requires knowledge of the molecular players involved and a quantitative description of their biochemical interactions, as well as the mechanical processes underlying polarity establishment. PolarNet brings together academic and private partners from 7 European countries to establish a multidisciplinary, intersectoral training and research programme that will study the basic principles of cell polarity. The research will combine complementary model systems ranging from fungi and cultured mammalian cells to whole organisms, and employ a broad set of approaches such as advanced genetics, protein biochemistry, high-resolution live imaging and image analysis, biophysics and theoretical modelling. This setting provides an opportunity to train early stage researchers in a unique combination of experimental and theoretical approaches. This will provide an excellent starting point for a successful career in the rapidly expanding field of multidisciplinary or ‘integrative’ biology. Training Europe’s next generation of scientists at the forefront of cell and organismal polarity research is crucial for progress in several medically important fields, including cancer research and stem cell biology. The tight collaboration with non-academic partners will strengthen the technological base of different projects and provide early stage researchers with insights into the translation potential of the performed studies and the career development opportunities in biomedical industry.

Keywords Cell Polarity
Financed by Commission of the European Union

Cooperations ()

  ID Kreditinhaber Kooperationspartner Institution Laufzeit - von Laufzeit - bis
3693571  Spang, Anne  Van den Heuvel, Sonder, Prof.  Developmental Biology, Department of Biology, Faculty of Science, Utrecht University  01.10.2015  30.09.2019 
3693580  Spang, Anne  Boxem, Mike, Prof.  Developmental Biology, Department of Biology, Faculty of Science, Utrecht University   01.10.2015  30.09.2019 
3693581  Spang, Anne  Arkowitz, Robert, Prof.  CNRS, University of Nice  01.10.2015  30.09.2019 
   

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