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KTI: cancer therapy based on bacterial protein delivery
Third-party funded project
Project title KTI: cancer therapy based on bacterial protein delivery
Principal Investigator(s) Nigg, Erich
Co-Investigator(s) Ittig, Simon Josef
Organisation / Research unit Departement Biozentrum / Cell Biology (Nigg)
Project start 01.09.2015
Probable end 31.08.2017
Status Completed
Abstract

Bacteria offer an ideal vehicle to deliver cargo to cancer cells as they preferentially grow within solid tumors. We have developed a technology based on a bacterial nano-needle to directly inject proteins into cancer cells and have obtained very promising results in delivering toxic proteins to cancer cells. Our aim is to optimize this system and to validate its efficacy in murine models of cancer. Our vision is to bring this novel treatment strategy into clinicial practice.

Financed by Innovation Promotion Agency CTI
   

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29/03/2024