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KTI: cancer therapy based on bacterial protein delivery
Third-party funded project |
Project title |
KTI: cancer therapy based on bacterial protein delivery |
Principal Investigator(s) |
Nigg, Erich
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Co-Investigator(s) |
Ittig, Simon Josef
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Organisation / Research unit |
Departement Biozentrum / Cell Biology (Nigg) |
Project start |
01.09.2015 |
Probable end |
31.08.2017 |
Status |
Completed |
Abstract |
Bacteria offer an ideal vehicle to deliver cargo to cancer cells as they preferentially grow within solid tumors. We have developed a technology based on a bacterial nano-needle to directly inject proteins into cancer cells and have obtained very promising results in delivering toxic proteins to cancer cells. Our aim is to optimize this system and to validate its efficacy in murine models of cancer. Our vision is to bring this novel treatment strategy into clinicial practice. |
Financed by |
Innovation Promotion Agency CTI
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29/03/2024
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