Anniversary of the discovery of sec mutants by Novick and Schekman

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Anniversary of the discovery of sec mutants by Novick and Schekman

JournalArticle (Originalarbeit in einer wissenschaftlichen Zeitschrift)

ID	3120390
Author(s)	Spang, A.
Author(s) at UniBasel	Spang, Anne
Year	2015
Year: comment	2015
Title	Anniversary of the discovery of sec mutants by Novick and Schekman
Journal	Molecular Biology of the Cell
Volume	26
Number	10
Pages / Article-Number	1783-5
Abstract	This year marks the 35th anniversary of the isolation of 23 SEC genes. These genes all encode key regulators of the secretory pathway, and much of our knowledge of the secretory pathway is based on this initial discovery. The identification of the SEC genes is a result of combining genetics, biochemistry, and electron microscopy in a very clever way. Scientists have been busy ever since seeking to understand the function and regulation of these genes and to identify further key players in the process. Although most of the machinery acting along the secretory pathway is known and its function generally understood, knowledge of regulation of the pathway under various conditions is still scarce and will keep researchers busy for years to come.
Publisher	American Society for Cell Biology
ISSN/ISBN	1059-1524 ; 1939-4586
edoc-URL	http://edoc.unibas.ch/dok/A6381826
Full Text on edoc	Available
Digital Object Identifier DOI	10.1091/mbc.E14-11-1511
PubMed ID	http://www.ncbi.nlm.nih.gov/pubmed/25972202
ISI-Number	WOS:000354413000001
Document type (ISI)	Historical Article, Journal Article

24/04/2024

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