An octadentate bifunctional chelating agent for the development of stable zirconium-89 based molecular imaging probes
JournalArticle (Originalarbeit in einer wissenschaftlichen Zeitschrift)
 
ID 2845708
Author(s) Patra, Malay; Bauman, Andreas; Mari, Cristina; Fischer, Christiane A.; Blacque, Olivier; Haeussinger, Daniel; Gasser, Gilles; Mindt, Thomas L.
Author(s) at UniBasel Mindt, Thomas L.
Häussinger, Daniel
Year 2014
Title An octadentate bifunctional chelating agent for the development of stable zirconium-89 based molecular imaging probes
Journal Chemical Communications
Volume 50
Number 78
Pages / Article-Number 11523-11525
Abstract (89)Zr-based imaging agents hold great promise as novel radio-tracers in nuclear medicine. However, insufficient stability of currently used radiometal complexes in vivo is a safety concern for clinical applications. We herein report the first octadentate bifunctional chelating agent for the development of (89)Zr-labelled (bio)conjugates with improved stability.
Publisher Royal Society of Chemistry
ISSN/ISBN 0022-4936
edoc-URL http://edoc.unibas.ch/dok/A6348327
Full Text on edoc No
Digital Object Identifier DOI 10.1039/c4cc05558f
PubMed ID http://www.ncbi.nlm.nih.gov/pubmed/25132321
ISI-Number WOS:000341774200022
Document type (ISI) Article
 
   

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