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Identification and pre-clinical development of novel integrin modulators
Project funded by own resources
Project title Identification and pre-clinical development of novel integrin modulators
Principal Investigator(s) Krähenbühl, Stephan
Gygax, Daniel
Organisation / Research unit Bereich Medizinische Fächer (Klinik) / Klinische Pharmakologie (Krähenbühl),
Departement Pharmazeutische Wissenschaften / Pharmakologie (Krähenbühl)
Project start 01.01.2013
Probable end 31.12.2015
Status Completed
Abstract

Inhibitors of the Lymphocyte function-associated antigen 1 (LFA1) have been shown to modulate lymphocyte function and to act as immunosppressants. The aim of the study is to design novel modulators of LFA1 and to characterize these substances pharmacologically and toxicologically in vitro and in vivo in experimental animals.

KTI Project Nr. 15265.1 PFLS-LS

Financed by Other funds
   

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