A statistical shape model of the human second cervical vertebra
JournalArticle (Originalarbeit in einer wissenschaftlichen Zeitschrift)
ID 2743688
Author(s) Clogenson, Marine; Duff, John M.; Luethi, Marcel; Levivier, Marc; Meuli, Reto; Baur, Charles; Henein, Simon
Author(s) at UniBasel Lüthi, Marcel
Year 2015
Title A statistical shape model of the human second cervical vertebra
Journal International journal of computer assisted radiology and surgery
Volume 10
Number 7
Pages / Article-Number 1097-1107
Keywords Statistical shape model, Second cervical vertebra, Non-rigid image registration, Segmentation, Principal component analysis

Statistical shape and appearance models play an important role in reducing the segmentation processing time
of a vertebra and in improving results for 3D model development. Here, we describe the different steps in generating a
statistical shape model (SSM) of the second cervical vertebra (C2) and provide the shape model for general use by the sci-
entific community. The main difficulties in its construction are the morphological complexity of the C2 and its variabil-
ity in the population.

The input dataset is composed of manually segmented anonymized patient computerized tomography (CT)
scans. The alignment of the different datasets is done with the procrustes alignment on surface models, and then, the reg-
istration is cast as a model-fitting problem using a Gaussian process. A principal component analysis (PCA)-based model
is generated which includes the variability of the C2.

The SSM was generated using 92 CT scans. The resulting SSM was evaluated for specificity, compactness and
generalization ability. The SSM of the C2 is freely available to the scientific community in Slicer (an open source soft-
ware for image analysis and scientific visualization) with a module created to visualize the SSM using Statismo, a frame-
work for statistical shape modeling.

The SSM of the vertebra allows the shape variability of the C2 to be represented. Moreover, the SSM will
enable semi-automatic segmentation and 3D model generation of the vertebra, which would greatly benefit surgery

Publisher Springer
ISSN/ISBN 1861-6410
edoc-URL http://edoc.unibas.ch/dok/A6328780
Full Text on edoc Available
Digital Object Identifier DOI 10.1007/s11548-014-1121-x
ISI-Number WOS:000357278000009
Document type (ISI) Article

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