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NCCR SYNAPSY
Third-party funded project
Project title NCCR SYNAPSY
Principal Investigator(s) Scheiffele, Peter
Organisation / Research unit Departement Biozentrum / Cell Biology (Scheiffele)
Project start 01.10.2014
Probable end 30.09.2018
Status Completed
Abstract

Autism is a highly heterogeneous disorder with unknown etiology. Genetic risk factors are considered to be a major component. We hypothesize, that diverse autism-associated mutations result in a disruption of a small set of core pathways that are ultimately responsible for altered neuronal function. Moreover, we hypothesize that these alterations in neuronal function precipitate during a critical developmental window the abnormal development of specific neuronal circuits. Thus, definition of the critical developmental window and targeted interventions to restore normal neuronal function during this time should provide a promising approach towards therapeutic intervention.

Financed by Swiss National Science Foundation (SNSF)
   

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29/03/2024