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Stem cells: from epigenetics to microRNAs
JournalArticle (Originalarbeit in einer wissenschaftlichen Zeitschrift)
 
ID 2635034
Author(s) Cheng, Li-Chun; Tavazoie, Masoud; Doetsch, Fiona
Author(s) at UniBasel Doetsch, Fiona
Year 2005
Title Stem cells: from epigenetics to microRNAs
Journal Neuron
Volume 46
Number 3
Pages / Article-Number 363-7
Abstract The complexity and cellular diversity of the adult brain arises from the proliferation and differentiation of a small number of stem cells. The intrinsic state of stem cells depends on their spatial and temporal history and affects their responsiveness to extrinsic signals from the microenvironment. Stem cell self-renewal and differentiation along neuronal and glial lineages are defined by the dynamic interplay between transcription, epigenetic control, and posttranscriptional regulators, including microRNAs, whose key role in stem cell biology is just emerging.
Publisher Elsevier
ISSN/ISBN 0896-6273 ; 1097-4199
edoc-URL http://edoc.unibas.ch/50362/
Full Text on edoc No
Digital Object Identifier DOI 10.1016/j.neuron.2005.04.027
PubMed ID http://www.ncbi.nlm.nih.gov/pubmed/15882632
ISI-Number WOS:000229011400004
Document type (ISI) Journal Article, Review
 
   

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